Diaphragmatic Effects of Combined Infraclavicular Brachial Plexus Block and Suprascapular Nerve Block

NCT07640464 | Completed

• 1 other identifier: 2024-GUTF-028
• Study Type: observational
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study was conducted to evaluate the effects of a combined infraclavicular brachial plexus block and anterior suprascapular nerve block on diaphragmatic function in patients undergoing arthroscopic shoulder surgery. A total of 61 adult patients were enrolled in the study. Diaphragmatic excursion was assessed using ultrasonography both prior to block administration and 30 minutes following the procedure during normal and deep breathing. The primary objective was to assess changes in diaphragmatic excursion and determine the incidence of hemidiaphragmatic paralysis associated with this combined block technique. Secondary outcomes included block performance time, duration of postoperative analgesia, the need for additional intraoperative sedation or analgesia, the occurrence of adverse events, and levels of patient and surgeon satisfaction. The study sought to determine whether this regional anesthesia approach could provide effective anesthesia and analgesia while minimizing impairment of diaphragmatic function.

Conditions

Diaphragmatic Excursion; Hemidiaphragmatic Paralysis; Arthroscopic Shoulder Surgery

Keywords

Anterior Suprascapular Nerve Block; Infraclavicular Brachial Plexus Block; Diaphragmatic Excursion; Shoulder Arthroscopy; Regional Anesthesia

Outcome Measures

Primary Outcomes (1)

• Change in Diaphragmatic Excursion at 30 Minutes After Block Administration

  Diaphragmatic excursion measured by ultrasonography during normal and deep breathing before block administration and 30 minutes after block administration. The percentage change from baseline was calculated.

  30 minutes after block administration

Secondary Outcomes (6)

• Incidence of Hemidiaphragmatic Paralysis

  30 minutes after block administration

• Degree of Hemidiaphragmatic Paralysis

  30 minutes after block administration

• Block Performance Time

  From needle insertion to completion of the block procedure

• Additional Intraoperative Analgesia Requirement

  From surgical incision to the end of surgery

• Time to First Analgesic Requirement

  Up to 24 hours after surgery

Study Arms (1)

Patients Undergoing Arthroscopic Shoulder Surgery

Patients undergoing arthroscopic shoulder surgery who received a combined infraclavicular brachial plexus block and anterior suprascapular nerve block. Diaphragmatic excursion was evaluated using ultrasonography before and after block administration.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18-80 years with ASA physical status I-III undergoing elective arthroscopic shoulder surgery at Gazi University Faculty of Medicine Hospital. Eligible participants received ultrasound-guided combined infraclavicular brachial plexus block and anterior suprascapular nerve block. The study evaluated changes in diaphragmatic excursion measured by ultrasonography before and after block administration.

You may qualify if:

• Patients aged 18-80 years.
• ASA physical status I-III.
• Scheduled for elective arthroscopic shoulder surgery.
• Ability to provide written informed consent

You may not qualify if:

• Refusal to undergo peripheral nerve block.
• Pre-existing peripheral neuropathy.
• Known pulmonary, hepatic, or renal disease.
• Allergy to local anesthetics.
• Infection at the block site.
• Pre-existing neurological deficit.
• Body mass index (BMI) \> 40 kg/m².
• Coagulopathy.
• Sepsis.
• Previous surgery at the planned block site.
• Major psychiatric disorders.
• Inability to complete diaphragmatic ultrasonographic assessment.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University Faculty of Medicine Hospital

Ankara, Ankara, 06500, Turkey (Türkiye)

Location

Study Officials

• IRFAN GUNGOR, MD

  Gazi university faculty of medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiology Resident

Study Record Dates

• First Submitted: May 31, 2026
• First Posted: June 10, 2026
• Study Start: February 22, 2025
• Primary Completion: July 20, 2025
• Study Completion: July 20, 2025
• Last Updated: June 10, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)