Comparison of Costoclavicular and Lateral Sagittal Infraclavicular Blocks

NCT07386470 | Completed

• 1 other identifier: ICB-CC-LS-2022
• Study Type: interventional
• Target: 91
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized clinical study aims to compare the effects of two different ultrasound-guided infraclavicular brachial plexus block techniques-costoclavicular and lateral sagittal approaches-in patients undergoing forearm, wrist, or hand surgery. The primary objective of the study is to evaluate and compare the incidence of hemidiaphragmatic dysfunction associated with these two block techniques. Secondary outcomes include sensory and motor block characteristics, postoperative pain scores, analgesic requirements, and potential block-related complications. Eligible adult patients scheduled for elective forearm or hand surgery are randomly assigned to receive either a costoclavicular or a lateral sagittal infraclavicular nerve block using bupivacaine under ultrasound guidance. Standard general anesthesia and postoperative analgesia protocols are applied. The results of this study are expected to provide evidence on the relative safety and efficacy of these two infraclavicular block approaches, particularly regarding diaphragmatic function, and to help guide anesthesiologists in selecting the most appropriate regional anesthesia technique for upper extremity surgery.

Conditions

Hemidiaphragmatic Paralysis; Upper Extremity Surgery

Keywords

Infraclavicular brachial plexus block; hemidiaphragmatic paralysis; costoclavicular brachial plexus block

Outcome Measures

Primary Outcomes (1)

• Diaphragmatic excursion

  Diaphragmatic excursion measured by ultrasound during normal and deep breathing to asses the effect of costoclavicular and lateral sagittal infraclavicular block techniques.

  Baseline(pre-block) and 30 minutes after block performance.

Secondary Outcomes (2)

• Sensory and motor block onset time

  Within the first 30 minutes after block performance.

• Time to first postoperative analgesic requirement

  Within the first 24 hours postoperatively.

Study Arms (2)

Costoclavicular infraclavicular block

EXPERIMENTAL

Ultrasound-guided costoclavicular infraclavicular brachial plexus block

Procedure: Ultrasound-guided Infraclavicular block

Lateral sagittal infraclavicular block

ACTIVE COMPARATOR

Ultrasound-guided lateral sagittal infraclavicular brachial plexus block

Procedure: Ultrasound-guided Infraclavicular block

Interventions

Ultrasound-guided Infraclavicular block PROCEDURE

Ultrasound-guided infraclavicular brachial plexus block performed using either the costoclavicular or lateral sagittal approach with standardized local anesthetic volume.

Also known as: costoclavicular infraclavicular block, lateral sagital infraclavicular block

Costoclavicular infraclavicular block; Lateral sagittal infraclavicular block

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-80 years
• ASA physical status I-III
• Scheduled for forearm, wrist, or hand surgery
• Planned infraclavicular brachial plexus block

You may not qualify if:

• Refusal of regional anesthesia
• Known allergy to local anesthetics
• Infection at the block site
• Pre-existing neurological deficit in the operative limb
• Severe pulmonary disease
• Coagulopathy or sepsis
• BMI \> 40 kg/m²
• Psychiatric disorders

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University Faculty of Medicine, Department of Anesthesiology and Reanimation

Ankara, Ankara, 06560, Turkey (Türkiye)

Location

Study Officials

• Irfan Güngör, MD

  Gazi University Faculty of Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Professor

Model Details: This was a prospective, randomized, parallel group study comparing two ultrasound guided infraclavicular block techniques

Study Record Dates

• First Submitted: January 28, 2026
• First Posted: February 4, 2026
• Study Start: October 15, 2022
• Primary Completion: April 15, 2023
• Study Completion: April 15, 2023
• Last Updated: February 5, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)