Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars

NCT07633834 | Not Yet Recruiting

• 1 other identifier: 2991994
• Study Type: interventional
• Target: 28
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.

Conditions

Root Caries; Vertical Root Fracture

Outcome Measures

Primary Outcomes (1)

• • Regulation of clinical signs and symptoms

  Patient-reported outcomes, including satisfaction, masticatory efficiency, and oral comfort measured by a visual analog scale (VAS).

  12 months

Secondary Outcomes (1)

• Assessment of radiographic bone changes

  12 months

Study Arms (2)

Hemisection

EXPERIMENTAL

patients in this group will have hemi sectioning to their compromised mandibular molars

Procedure: hemi sectioning

dental implants

NO INTERVENTION

patients will undergo extraction and replaced with dental implants

Interventions

hemi sectioning PROCEDURE

one root will be extracted and the other root will be preserved

Hemisection

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Good oral hygiene and motivation for follow-up care.
• Ability to understand and sign informed consent.
• Localized Root/Periodontal Disease: Severe attachment loss or bone loss (e.g., severe localized periodontitis) affecting the mesial root, while the other root remains healthy.
• Furcation Involvement: Class II or III furcation involvements where the disease cannot be treated by conventional methods.
• Vertical root fracture confined to the mesial root.
• Non-treatable perforation in the mesial root.
• Extensive sub-gingival root caries affecting the mesial root.
• Extensive un-treatable internal and external root resorption related to the mesial root.

You may not qualify if:

• Uncontrolled systemic diseases (e.g., diabetes mellitus, bleeding disorders, immunosuppression).
• Fused or poorly shaped roots,
• Active periodontal or endodontic infection at adjacent teeth that may interfere with treatment outcomes.
• Severe bruxism or occlusal parafunction.
• History of radiation therapy in the head and neck region.
• Pregnancy or lactation.
• Poor compliance or inability to attend follow-up visits.
• Smoking more than 10 cigarettes per day.

Sponsors & Collaborators

• Ain Shams University: lead

MeSH Terms

Conditions

Root Caries

Condition Hierarchy (Ancestors)

Dental Caries; Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer at department of Endodontics

Study Record Dates

• First Submitted: May 24, 2026
• First Posted: June 8, 2026
• Study Start (Estimated): January 1, 2027
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): January 1, 2028
• Last Updated: June 8, 2026

Record last verified: 2026-05