Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars

NCT07608497 | Not Yet Recruiting

• 1 other identifier: 2072021
• Study Type: interventional
• Target: 28
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.

Conditions

Root Caries

Outcome Measures

Primary Outcomes (1)

• regression of clinical signs and symptoms and improvement in the bone radiographically

  Disappearance of signs and symptoms including tooth mobility, pain on percussion, functional success. from zero to 10 Visual analgue scale (VAS) will be used to measure the patients pain after the procedure where zero indicated no pain and 10 indicated intorable pain and the bone will be assessed Radiographically. regarding the implant 1ry and 2ndry stability using Any Check and mesiodistal radiographic bone changes.

  12 months

Study Arms (2)

root imputation

EXPERIMENTAL

patients in this group will do root amputation for the defective root in upper maxillary molar

Procedure: root amputation

dental implant

NO INTERVENTION

patients in this group will be directed to extraction and placement of dental implant

Interventions

root amputation PROCEDURE

only one root will be amputated and the rest of the molar will be preserved

root imputation

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients will be illegible for root amputation if they one or more of the following criteria:
• Severe vertical bone loss affecting only Mesio-buccal root of Maxillary molar.
• Through-and-through furcation involvement
• Vertical root fracture confined to a Mesio-buccal root of Maxillary molar.
• Extensive root caries affecting Mesio-buccal root of Maxillary molar.
• Endodontic failure or non- treatable perforation in Mesio-buccal root of Maxillary molar
• Extensive internal or external non- treatable root resorption related to Mesio-buccal root of Maxillary molar.
• Patients who do not meet the above criteria and present with Maxillary molars in more severely compromised conditions will be directed for extraction followed by dental implant placement.

You may not qualify if:

• \- Uncontrolled systemic disease, immunosuppression, recent bisphosphonate use, head and neck radiotherapy.
• Patient non-compliance or poor oral hygiene.
• Heavy smoking or inability to commit to maintenance.
• Root anatomy or interradicular bone that precludes predictable root amputation; insufficient bone for implant placement that cannot be reasonably augmented.

Sponsors & Collaborators

• Ain Shams University: lead

MeSH Terms

Conditions

Root Caries

Interventions

Apicoectomy

Condition Hierarchy (Ancestors)

Dental Caries; Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Oral Surgical Procedures; Surgical Procedures, Operative; Endodontics; Dentistry

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Study Record Dates

• First Submitted: May 13, 2026
• First Posted: May 27, 2026
• Study Start (Estimated): January 1, 2027
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): January 1, 2028
• Last Updated: May 27, 2026

Record last verified: 2026-05