NCT07632612

Brief Summary

objective of this randomized controlled trial is to examine the efficacy of both tensioner and slider neurodynamic approaches in patients suffering from sciatica. This study seeks to establish which approach is more efficacious in alleviating pain intensity, disability functional, and mobility. The results of this study will assist physical therapists in making an informed decision on the type of neurodynamic therapy for their patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
1mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress60%
Jun 2026Sep 2026

First Submitted

Initial submission to the registry

June 2, 2026

Completed
1 day until next milestone

Study Start

First participant enrolled

June 3, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 8, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 3, 2026

Expected
7 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 10, 2026

Last Updated

June 8, 2026

Status Verified

May 1, 2026

Enrollment Period

3 months

First QC Date

June 2, 2026

Last Update Submit

June 2, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Pain intensity

    will be measured using VAS

    Baseline to Week 8

  • Functional disability

    measured using Oswestry Disability Index (ODI)

    Baseline to week 8

Secondary Outcomes (2)

  • Hip range of motion

    Baseline to week 8

  • Lumbar flexion Range of Motion

    Baseline to Week 8

Study Arms (2)

Slider Neurodynamic Technique Group

EXPERIMENTAL

Participants will receive slider neurodynamic mobilization techniques along with conventional physiotherapy management.

Other: Slider Neurodynamic Technique Group

Tensioner Neurodynamic Technique Group

ACTIVE COMPARATOR

Participants will receive tensioner neurodynamic mobilization techniques along with conventional physiotherapy management.

Other: Tensioner Neurodynamic Technique Group

Interventions

will receive slider neurodynamic mobilization techniques along with conventional physiotherapy management.

Slider Neurodynamic Technique Group

will receive tensioner neurodynamic mobilization techniques along with conventional physiotherapy management.

Tensioner Neurodynamic Technique Group

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with radicular pain persisting for 12 weeks to 1 year, with no acute episode in the last 4 weeks
  • Unilateral symptoms radiating below the buttock to thigh, knee, or lower leg
  • Positive Slump Test
  • Positive Straight Leg Raise (SLR) test above 45°
  • Functional limitation during activities such as walking or lifting

You may not qualify if:

  • BMI \< 20 kg/m² or \> 30 kg/m²
  • Previous history of spinal surgery
  • Presence of red flags (significant motor/sensory loss, altered reflexes, or bowel/bladder dysfunction)
  • Peripheral neuropathy
  • History of vertebral fracture or significant spinal/limb trauma
  • Systemic diseases (e.g., diabetes mellitus, cardiovascular, or renal disease)
  • Progressive neurological deficits (motor weakness, sensory loss, reflex changes)
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ibadat International Hospital

Rawalpindi, Punjab Province, Pakistan

RECRUITING

MeSH Terms

Conditions

Sciatica

Condition Hierarchy (Ancestors)

Sciatic NeuropathyMononeuropathiesPeripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesNeuralgiaPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Sojla Bashir, DPT, MSPT MSK

CONTACT

Sidra Hanif, DPT, MSNMPT, PhD PT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 2, 2026

First Posted

June 8, 2026

Study Start

June 3, 2026

Primary Completion (Estimated)

September 3, 2026

Study Completion (Estimated)

September 10, 2026

Last Updated

June 8, 2026

Record last verified: 2026-05

Locations