Neurodynamic Moblization Versus Mulligan on Pain and Functional Abilities in Patients With Chronic Discogenic Sciatica

NCT07050108 | Completed

• 1 other identifier: P.T.REC/012/004903
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the present study to compare between the effect of neurodynamic moblizaton and Mulligan SNAG's moblization on patients with chronic unilateral discogenic sciatica.

Conditions

Sciatica; Discogenic Pain

Keywords

Neurodynamic Moblization; mulligan therapy; sciatica

Outcome Measures

Primary Outcomes (2)

• pressure pain threshold

  ALgometer offer real-time visual \& auditory feedback to control \& monitor applied pressure rates to measure pressure pain threshold.

  up to four weeks

• pain intensity

  Sciatica Bothersomeness Index will be used to assess pain intensity. An index based on patients reporting of symptoms which reflects the troubled patient is going through with his sciatica symptoms. Items from the Sciatica Bothersomeness Index (0 = none to 6 = extremely) were used to establish values for paresthesia, weakness and leg pain.

  up to four weeks

Secondary Outcomes (2)

• Range of motion assessment of straight leg raise

  up to four weeks

• disability

  up to four weeks

Study Arms (3)

neurodynamic mobilization

EXPERIMENTAL

twenty two patients will receive neurodynamic mobilization and selected physical therapy program three times a week for four weeks

Other: neurodynamic mobilization; Other: selected physical therapy program

Mulligan therapy

EXPERIMENTAL

twenty two patients will receive mulligan therapy and selected physical therapy program three times a week for four weeks

Other: mulligan therapy; Other: selected physical therapy program

selected physical therapy program

ACTIVE COMPARATOR

twenty two patients will selected physical therapy program three times a week for four weeks

Other: selected physical therapy program

Interventions

neurodynamic mobilization OTHER

the patients will receive neurodynamic mobilization in the form of opening technique which include; static opening and dynamic opening. also, sliding and tensioning technique+ selected physical therapy program

neurodynamic mobilization

mulligan therapy OTHER

sustained natural apophyseal glide SNAGs are mobilisation techniques and are used as part of the Mulligan Concept+ selected physical therapy program The patient position is stitting on the edage of the plenth non weight bearing position. The therapist will stand behind the patient, the therapist will apply SNAG for 3 repetitions during the initial screening session,the patient will be asked to lean forwared while applying the technique .the therapist apply onle from fove to seven repetitions.patients who experienced no worsening or showed improvement of pain and ROM were considered good indication for the effectivness of treatment .

Mulligan therapy

selected physical therapy program OTHER

The program of therapeutic exercises consisted of upper and lower back exercises. Each exercise will repeat from ten to thirty times, three repetitions in three sets with rest one to two minutes between the sets. The repetition of each exercise vary according to the physical ability of each patient. Lower back strengthening exercises: From prone lying position, the patient will asked to raise one lower limb then the other then both lower limbs+ TENS and US

Mulligan therapy; neurodynamic mobilization; selected physical therapy program

Eligibility Criteria

• Age: 35 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• All the patients diagnosed as lumbar radiculopathy (L5-S1) for at least six months. Diagnosis was confirmed by physical, neurological examination (motor assessment, sensory assessment, reflexes) and radiological assessment (CT or MRI).
• All patients has second grade of disc bulge which will detect from T2 axial view of MRI according to Fardon and Milette
• All patients has unilateral radiculopathy and pain in the distribution of scaitic nerve.
• The age of the patients will range from 35 to 50years . Their body mass index will range between( 22-25)

You may not qualify if:

• Bilateral and multilevel disc prolapse or bilateral radtadiating pain
• acute pain (pain less than three months).
• Presence of active infection in lumbar spine.
• Any other spinal deformities.
• Postoperative cases.
• Cauda equine lesion.
• Neoplasmic.
• Spinal stenosis.
• Mechanical low back pain.
• Failed back syndrome.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of physical therapy, Cairo University

Cairo, Egypt

Location

MeSH Terms

Conditions

Sciatica

Condition Hierarchy (Ancestors)

Sciatic Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Neuralgia; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: opaque sealed envelope
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator : Asmaa ibrahim Attia

Model Details: neurodynamic ans mulligan

Study Record Dates

• First Submitted: June 25, 2025
• First Posted: July 3, 2025
• Study Start: August 10, 2025
• Primary Completion: January 10, 2026
• Study Completion: January 28, 2026
• Last Updated: March 5, 2026

Record last verified: 2026-03

Locations

EG (1)