NCT07627581

Brief Summary

This randomized crossover pilot clinical trial evaluated the effects of two self-administered physiotherapy techniques in people with hamstring tightness and a history of non-specific low back pain. Participants were randomly assigned to one of two treatment sequences. One sequence performed self-myofascial release using a foam roller first, followed by a one-month washout period, and then performed a self-administered neurodynamic sliding technique. The other sequence performed the neurodynamic sliding technique first, followed by a one-month washout period, and then performed the foam roller intervention. The main objective of the study was to compare the effects of both interventions on hamstring flexibility. Secondary outcomes included active knee extension range of motion, dynamic balance, pressure pain threshold, hamstring and gluteus maximus strength, and low back pain intensity.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable low-back-pain

Timeline
2mo left

Started Jun 2026

Shorter than P25 for not_applicable low-back-pain

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress23%
Jun 2026Aug 2026

First Submitted

Initial submission to the registry

May 30, 2026

Completed
2 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 4, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Last Updated

June 8, 2026

Status Verified

May 1, 2026

Enrollment Period

2 months

First QC Date

May 30, 2026

Last Update Submit

June 4, 2026

Conditions

Keywords

foam rollerSelf-myofascial releaseNeurodynamic slidingHamstring flexibilityLow back painCrossover trial

Outcome Measures

Primary Outcomes (1)

  • Change in Hamstring Flexibility Measured With the Straight Leg Raise Test

    Hamstring flexibility will be assessed using the Straight Leg Raise test. The test will be performed with the participant in the supine position, and hip flexion range of motion will be measured in degrees using a goniometer. Higher values indicate greater hamstring flexibility.

    Baseline of each intervention period, 24 hours after completing each intervention, and 7 days after each intervention

Secondary Outcomes (4)

  • Change in Hamstring Flexibility Measured With the Active Knee Extension Test

    Baseline of each intervention period, 24 hours after completing each intervention, and 7 days after each intervention

  • Change in Dynamic Balance Measured With the Y-Balance Test

    Baseline of each intervention period, 24 hours after completing each intervention, and 7 days after each intervention

  • Change in Pressure Pain Threshold

    Baseline of each intervention period, 24 hours after completing each intervention, and 7 days after each intervention

  • Change in Low Back Pain Intensity

    Baseline of each intervention period, 24 hours after completing each intervention, and 7 days after each intervention

Study Arms (2)

Foam Roller First, Then Neurodynamic Sliding

EXPERIMENTAL

Participants assigned to this sequence will first perform self-myofascial release using a foam roller on the hamstring muscles. After a one-month washout period, they will perform the self-administered neurodynamic sliding technique.

Other: Self-Myofascial Release Using a Foam RollerOther: Self-Administered Neurodynamic Sliding Technique

Neurodynamic Sliding First, Then Foam Roller

EXPERIMENTAL

Participants assigned to this sequence will first perform the self-administered neurodynamic sliding technique. After a one-month washout period, they will perform self-myofascial release using a foam roller on the hamstring muscles.

Other: Self-Myofascial Release Using a Foam RollerOther: Self-Administered Neurodynamic Sliding Technique

Interventions

Participants will perform bilateral self-myofascial release of the hamstring muscles using a foam roller. The technique will be performed for 2 minutes per leg over three consecutive days.

Foam Roller First, Then Neurodynamic SlidingNeurodynamic Sliding First, Then Foam Roller

Participants will perform a seated self-administered neurodynamic sliding technique over three consecutive days. The intervention will consist of 3 sets of 20 repetitions, with 20 seconds of rest between sets.

Foam Roller First, Then Neurodynamic SlidingNeurodynamic Sliding First, Then Foam Roller

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men and women aged 16 years or older.
  • History of non-specific low back pain during the previous three months and/or recurrent or chronic non-specific low back pain.
  • Limited hamstring flexibility, defined as hamstring tightness with 75 degrees or less of hip flexion with knee extension during the Straight Leg Raise test.
  • No previous surgery involving the spine or lower limb.
  • No hamstring stretching exercises performed in the weeks prior to participation.
  • Ability and willingness to provide informed consent.
  • Availability to perform both self-administered physiotherapy techniques according to the study protocol.

You may not qualify if:

  • Pregnancy or breastfeeding.
  • History of hamstring muscle or tendon injury during the previous year.
  • Lumbar or lower-limb neurological deficits.
  • Lower-limb length discrepancy.
  • Specific spinal pathology, including tumor, infection, fracture, or inflammatory disease.
  • History of lumbar disc herniation.
  • History of whiplash injury.
  • Any contraindication to physical exercise.
  • Menstrual pain at the time of assessment or intervention.
  • Scheduled surgery during the intervention or follow-up period.
  • History of cardiac disease.
  • Incomplete or incorrectly completed questionnaires or missing assessment data.
  • Refusal to complete part or all of the study intervention.
  • Development of a low back pain episode during the study intervention.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clínica Universitaria Salus Infirmorum, Universidad Pontificia de Salamanca

Madrid, Madrid, 28015, Spain

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Sara Perpiña Martínez, PT, PhD

    Pontifical University of Salamanca

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sara Perpiña Martínez, PT, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The outcomes assessor will be masked to the intervention sequence assigned to each participant. Due to the nature of the interventions, participants and the physiotherapist supervising the interventions cannot be masked.
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Participants will be randomly assigned to one of two intervention sequences. In one sequence, participants will first perform self-myofascial release using a foam roller, followed by a one-month washout period, and then perform the self-administered neurodynamic sliding technique. In the other sequence, participants will first perform the self-administered neurodynamic sliding technique, followed by a one-month washout period, and then perform self-myofascial release using a foam roller.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator and Professor of Physiotherapy

Study Record Dates

First Submitted

May 30, 2026

First Posted

June 4, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

August 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

June 8, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because the study dataset contains health-related information collected in a small pilot trial. Data will be pseudonymized and stored according to applicable data protection regulations, but no formal data sharing plan has been established.

Locations