Low Blood Flow Restriction Training on Low Back Pain

NCT07576101 | Not Yet Recruiting

• 1 other identifier: Muzammel Fatima
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this randomized controlled trial is to find the effectiveness of low load blood restriction training on improving hamstring muscle strength, alleviating pain and reducing functional disability in nonspecific low back pain patients

Conditions

Low Back Pain

Keywords

Blood Flow Restriction; Low Back Pain; hamstring muscle strength

Outcome Measures

Primary Outcomes (3)

• Manual Muscle Testing (MMT)

  MMT is the most commonly used method for documenting impairments in muscle strength. The examiner in the application of force to the subject's resistance evaluates the muscles being studied as subjectively "weak" or "strong" on a 5-point scale.

  : 4 weeks

• Numeric Pain Rating Scale (NPRS)

  The NPRS is a segmented numeric version of the visual analog scale which is used to assess pain. It scores ranges from 0-10, 0 means No pain and 10 means Severe pain. Patient will be asked to verbally report the pain score.

  4 weeks

• Oswestry Disability Index (ODI)

  The Oswestry Disability Index (ODI) a patient-completed questionnaire which gives a subjective percentage score of pain-related disability in persons with low back pain (LBP). The Oswestry Disability Index (ODI) addresses a broader concept of disability than that directly related to pain intensity

  4 weeks

Study Arms (2)

Low blood flow restriction training

OTHER

Low blood flow restriction training

Other: Low Blood Flow Restriction Training

Conventional PT

OTHER

Conventional PT

Other: Conventional PT

Interventions

Conventional PT OTHER

All interventional participants will attend 3 weekly 45-50 minutes sessions for a duration of four week. Group B will receive electrical hot packs for 8-10 minutes followed by myofascial releases using a foam roller for 5-8 minutes primarily targeting the hamstring. Total 4 sets of each exercise (Glute bridge exercises, lumbar extension exercise, straight leg raise from prone and table top exercises) with 20 repetitions will be performed. Allow 30-60 sec rest interval

Conventional PT

Low Blood Flow Restriction Training OTHER

All interventional participants will attend 3 weekly 45-50 minutes sessions for a duration of four week. Group A will receive electrical hot packs for 8-10 minutes followed by myofascial releases using a foam roller for 5-8 minutes primarily targeting the hamstring. For low load BFR training therapist will place sphygmomanometer cuff 10cm below the inguinal crease on the upper 3rd of thigh. The inflation pressure range will be individualized intended to produce complete arterial occlusion measured manually by palpating posterior tibial artery until the pulse will be felt no longer. Deflate the pressure cuff up to 60-80% of the AOP to create partial arterial occlusion. Total 4 sets of each exercise (Hamstring curls, Single leg hamstring curls on stability ball, standing hamstring curl, hamstring curl with sliders) with 30 repetitions in 1st set and then 15 repetitions in remaining 3 sets. Allow 30-60 sec rest interval between sets

Low blood flow restriction training

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Participants falling in this category would be recruited into the study.
• Both gender
• Age is between 18-45 years
• Individuals with pain localized posteriorly below the costal margin and above the inferior gluteal folds for more than 12 weeks
• A score greater than or equal to 4/10 on Numeric Pain Rating Scale (NPRS)
• Hamstring muscle strength graded between (3- to 4) on MMT
• Proximal thigh circumference between (27.0 cm to 56.0 cm), measured 10cm below the inguinal crease
• Eligible for BFR training as per the Blood Flow Restriction Blood Flow Training Questionnaire

You may not qualify if:

• Participants falling in this category would be excluded from the study.
• Patients of spinal stenosis, disc herniation spondylolisthesis, spondylosis or osteoporosis will be excluded
• Participants had a history of hip or lower extremity pathology requiring medical or surgical intervention.
• History of venous thromboembolism (VTE), clotting or other hematologic disorder
• Peripheral arterial disease, hypertension (blood pressure \>140/90 mm Hg), coronary artery disease
• Current Pregnancy
• Patients who had difficulties in exercise performance due to mental problems.
• Spinal cord infection like Cauda equina syndrome

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

National Institute Of Rehabilitation Medicine G-8/2, Islamabad

Islamabad, 46000, Pakistan

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• KINZA ANWAR, MS-OMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

KINZA ANWAR, MS-OMPT

CONTACT

+92-3239735427; kinza.anwar@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2026
• First Posted: May 8, 2026
• Study Start: May 2, 2026
• Primary Completion (Estimated): May 2, 2027
• Study Completion (Estimated): May 12, 2027
• Last Updated: May 8, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)