Impact of Depression Severity on Sexual Dysfunction

NCT07627477 | Active Not Recruiting

• 1 other identifier: Soh-Med-26-4-7MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Assess the relationship and the prevalence…" "To determine the prevalence of erectile dysfunction and premature ejaculation among depressed male patients and evaluate their association with depression severity."

Conditions

Depression; Erectile Dysfunction; Premature Ejaculation

Keywords

Depression severity; Depression; Premature Ejaculation; Erectile Dysfunction

Outcome Measures

Primary Outcomes (2)

• Assessment of Depression severity in premature Ejaculation patients

  Depression severity will be assessed using the 17-item Hamilton Depression Rating Scale (HAM-D-17), a clinician-administered instrument widely used to evaluate depressive symptoms. The total score ranges from 0 to 52, with higher scores indicating greater severity of depression. Scores will be analyzed to determine the relationship between depression severity and the occurrence and severity of premature ejaculation among male psychiatric patients using premature Ejaculation severity scale PEDS Interpretation of HAM-D 0-7: Normal 8-16: Mild depression 17-22: Moderate depression * 23: Severe depression Scoring of PEDS ≤ 8: No PE 9-10: Probable PE * 11: PE likely present Higher scores indicate greater severity of premature ejaculation.

  6 months

• Assessment of Depression severity in Erectile Dysfunction patients

  Depression severity will be assessed using the 17-item Hamilton Depression Rating Scale (HAM-D-17), a clinician-administered instrument widely used to evaluate depressive symptoms. The total score ranges from 0 to 52, with higher scores indicating greater severity of Depression.Scores will be analyzed to determine the relationship between depression severity and the occurrence and severity of Erectile Dysfunction among male psychiatric patients using the 5-item International Index of Erectile Function (IIEF-5), . Total scores range from 5 to 25, with lower scores indicating more severe erectile dysfunction. Interpretation of HAM-D 0-7: Normal 8-16: Mild depression 17-22: Moderate depression ≥23: Severe depression Interpretation of IIEF 22-25: No erectile dysfunction 17-21: Mild erectile dysfunction 12-16: Mild to moderate erectile dysfunction 8-11: Moderate erectile dysfunction 5-7: Severe erectile dysfunction.

  6 months

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Male married patients diagnosed with depressive disorder according to DSM5

You may qualify if:

• Married male pt aged 25\_60yrs
• Clinically diagnosed with depressive disorder DSM5
• sexually active in the past 6 months

You may not qualify if:

• pts with major medical or neurological disorders known to be impaired sexual activity
• History of substance use disorder
• Pts receiving medications known to cause sexual Dysfunction except antidepressants
• Pts with primary sexual Dysfunction prior to the onset of Depression

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag faculty of medicine

Sohag, Egypt

Location

MeSH Terms

Conditions

Depression; Erectile Dysfunction; Premature Ejaculation

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Sexual Dysfunction, Physiological; Male Urogenital Diseases; Sexual Dysfunctions, Psychological; Mental Disorders; Ejaculatory Dysfunction

Study Officials

• Ahmed L Elsayed, MD

  Faculty of medicine sohag university

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: May 7, 2026
• First Posted: June 4, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): June 1, 2027
• Last Updated: June 4, 2026

Record last verified: 2026-05

Locations

EG (1)