The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation

NCT07442396 | Recruiting

• 1 other identifier: Uskudar93
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to investigate the effectiveness of exercise in the treatment of erectile dysfunction and premature ejaculation.

Conditions

Erectile Dysfunction; Premature Ejaculation

Outcome Measures

Primary Outcomes (2)

• International Index of Erectile Dysfunction

  Mean change in International Index of Erectile Dysfunction scores. There are five specific areas addressed including Erectile Function (questions:1-5 \& 15;score range: 0-5, maximum score:30); Orgasmic Function (questions:9-10; score range:0-5; maximum score:10); Sexual desire (questions:11-12; score range:1-5; maximum score:10); Intercourse satisfaction (questions:6-8; score range:0-5; maximum score:15); Overall satisfaction (questions:13-14; score range:1-5; maximum score:10). The lower the score represents greater dysfunction within each domain.

  10 weeks

• Premature Ejaculation Diagnostic Tool

  it was developed by Symonds et al. (2007) to better define premature ejaculation for use in clinical studies, this is a 5-point Likert-type scale consisting of 5 items. The scale was adapted to Turkish by Serefoglu et al. (2009). The highest score that can be obtained from the scale is 20.0 and the lowest score is 0.0. Scores higher than 11 are defined as "Premature Ejaculation", scores of 9-10 are defined as "possible Premature Ejaculation", and scores of eight or less are defined as "no Premature Ejaculation".

  10 weeks

Study Arms (2)

control group

ACTIVE COMPARATOR

only patients who receive medical treatment and informational training

Other: control

exercise group

EXPERIMENTAL

Patients who receive pelvic floor exercises in addition to medical treatment and education.

Other: exercise

Interventions

control OTHER

Patients in the control group will be followed with normal conventional medical treatment.

Also known as: medical treatment

control group

exercise OTHER

Participants in the exercise group will undergo an 8-week, 3-day-a-week exercise program.

Also known as: Pelvic Floor Exercise Group

exercise group

Eligibility Criteria

• Age: 25 Years - 45 Years
• Gender Eligibility Details: diseases seen in men
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male individuals aged 25-45 years
• Individuals diagnosed with erectile dysfunction and premature ejaculation
• Individuals who voluntarily agree to participate in the study and sign the informed consent form
• Individuals who have the physical and cognitive capacity to participate in pelvic floor physiotherapy applications

You may not qualify if:

• Individuals with a history of surgery in the pelvic region
• Individuals with a diagnosis of neurological disease or neurological disorder that may affect pelvic floor muscle function
• Presence of active infection, inflammation, or painful pathology in the pelvic region
• Individuals who regularly use medications that significantly affect sexual function
• Individuals with serious psychiatric illness or cognitive impairment that may hinder study compliance

Sponsors & Collaborators

• Uskudar University: lead

Study Sites (1)

Uskudar university

Istanbul, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Yaacov D, Nelinger G, Kalichman L. The Effect of Pelvic Floor Rehabilitation on Males with Sexual Dysfunction: A Narrative Review. Sex Med Rev. 2022 Jan;10(1):162-167. doi: 10.1016/j.sxmr.2021.02.001. Epub 2021 Apr 27.

  PMID: 33931383 BACKGROUND

• Sahin E, Brand A, Cetindag EN, Messelink B, Yosmaoglu HB. Pelvic physical therapy for male sexual disorders: a narrative review. Int J Impot Res. 2025 Dec;37(12):941-949. doi: 10.1038/s41443-025-01034-5. Epub 2025 Feb 27.

  PMID: 40016382 BACKGROUND

• Niu C, Ventus D, Wen G, Santtila P. Associations between self-reports of physical activity, interoceptive awareness, autonomic regulation, premature ejaculation, and erectile dysfunction in Chinese men. Int J Impot Res. 2025 Dec;37(12):992-1001. doi: 10.1038/s41443-025-01072-z. Epub 2025 Apr 19.

  PMID: 40251377 BACKGROUND

MeSH Terms

Conditions

Erectile Dysfunction; Premature Ejaculation

Interventions

Exercise

Condition Hierarchy (Ancestors)

Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Sexual Dysfunction, Physiological; Male Urogenital Diseases; Sexual Dysfunctions, Psychological; Mental Disorders; Ejaculatory Dysfunction

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Parsa Keihani

  Uskudar University

  STUDY CHAIR

Central Study Contacts

Ömer ŞEVGİN

CONTACT

+905069787535; omer.sevgin@uskudar.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc.Prof.Dr.

Study Record Dates

• First Submitted: February 25, 2026
• First Posted: March 2, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): May 30, 2026
• Study Completion (Estimated): July 10, 2026
• Last Updated: March 3, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)