Erector Spina Plane Block Versus Modified Thoracoabdominal Nerve Block After Laparoscopic Cholecystectomy

NCT07624058 | Recruiting

• 1 other identifier: 0109414
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

direct comparisons between ESPB and M-TAPA for postoperative analgesia after LC remain limited. This is an important area of clinical interest because the two blocks differ significantly in their anatomical targets, mechanism of analgesia, and likely dermatomal coverage. The ESPB provides analgesia through paravertebral spread affecting both dorsal and ventral rami, thereby offering posterior and visceral pain relief, whereas M-TAPA directly targets the thoracoabdominal nerves, resulting in better anterior and lateral abdominal wall analgesia. Understanding which technique offers superior or more balanced analgesia could help to optimise regional anaesthesia strategies in LC and to improve patient outcomes.

Conditions

Erector Spinae Block; Laparoscopic Cholecystectomy; Modified Thoracoabdominal Nerve Block

Keywords

pain control; erector spinae block

Outcome Measures

Primary Outcomes (1)

• Time to First Analgesic request

  minutes

  postoperative day 1

Secondary Outcomes (4)

• Total Nalbuphine consumption

  postoperative day 1

• Visual analogue score

  postoperative day1

• Quality of postoperative recovery

  postoperative day 1

• Incidence of complications or adverse events

  postoperative day 5

Study Arms (2)

group 1

ACTIVE COMPARATOR

patients will receive bilateral ESP block

Other: bilateral ESP block

group 2

EXPERIMENTAL

patients will receive bilateral M-TAPA block

Other: bilateral M-TAPA block

Interventions

bilateral ESP block OTHER

bilateral ESP block with injection of 20 ml 0.25% bupivacaine.

group 1

bilateral M-TAPA block OTHER

bilateral M-TAPA block with injection of 20 ml of 0.25% bupivacaine.

group 2

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age: between 30 - 65
• American Society of Anaesthesiologists physical status: I- III
• Body mass index: 18-35 kg.m-2

You may not qualify if:

• Patient Refusal
• Allergy to local anaesthetic agents.
• Skin infection at the site of injection.
• Coagulopathy.
• Diabetes Mellitus

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Alexandria University

Alexandria, Egypt

RECRUITING

Related Publications (1)

• Tulgar S, Selvi O, Thomas DT, Deveci U, Ozer Z. Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) provides effective analgesia in abdominal surgery and is a choice for opioid sparing anesthesia. J Clin Anesth. 2019 Aug;55:109. doi: 10.1016/j.jclinane.2019.01.003. Epub 2019 Jan 9. No abstract available.

  PMID: 30639940 RESULT

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• sarah m elgamal, MD

  Alexandria University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

sarah m elgamal, MD

CONTACT

01005496440; sarahelgamal1990@yahoo.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Study Record Dates

• First Submitted: May 29, 2026
• First Posted: June 3, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): March 1, 2027
• Last Updated: June 3, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)