Erector Spinae Plane Block Versus Modified Thoracoabdominal Nerve Block For Pain Control After Laparoscopic Cholecystectomy
Sponsor study identifier
interventional
50
1 country
1
Study Start
April 1, 2026
Actual (reported)Primary Completion
December 1, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
direct comparisons between ESPB and M-TAPA for postoperative analgesia after LC remain limited. This is an important area of clinical interest because the two blocks differ significantly in their anatomical targets, mechanism of analgesia, and likely dermatomal coverage. The ESPB provides analgesia through paravertebral spread affecting both dorsal and ventral rami, thereby offering posterior and visceral pain relief, whereas M-TAPA directly targets the thoracoabdominal nerves, resulting in better anterior and lateral abdominal wall analgesia. Understanding which technique offers superior or more balanced analgesia could help to optimise regional anaesthesia strategies in LC and to improve patient outcomes.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 1, 2026
Actual (reported)May 29, 2026
Actual (reported)June 3, 2026
Actual (reported)December 1, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Time to First Analgesic request
minutes
postoperative day 1
Total Nalbuphine consumption
postoperative day 1
Visual analogue score
postoperative day1
Quality of postoperative recovery
postoperative day 1
Incidence of complications or adverse events
postoperative day 5
patients will receive bilateral ESP block
patients will receive bilateral M-TAPA block
bilateral ESP block with injection of 20 ml 0.25% bupivacaine.
bilateral M-TAPA block with injection of 20 ml of 0.25% bupivacaine.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Alexandria University
Alexandria, Egypt
Tulgar S, Selvi O, Thomas DT, Deveci U, Ozer Z. Modified thoracoabdominal nerves block through perichondrial approach (M-TAPA) provides effective analgesia in abdominal surgery and is a choice for opioid sparing anesthesia. J Clin Anesth. 2019 Aug;55:109. doi: 10.1016/j.jclinane.2019.01.003. Epub 2019 Jan 9. No abstract available.
sarah m elgamal, MD
Alexandria University
First Submitted
May 29, 2026
First Posted
June 3, 2026
Study Start
April 1, 2026
Actual (reported)Primary Completion
December 1, 2026
EstimatedContact the study team to confirm eligibility.
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
March 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
June 3, 2026
Record last verified: 2026-05
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Source: ClinicalTrials.gov.
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