Home-Based Circuit Training in Adults With Obesity

NCT07619612 | Completed

• 2 other identifiers: HBCT-OB-2026Ratchadapisek Postdoctoral
• Study Type: interventional
• Target: 29
• Locations: 1 country
• Sites: 1

Brief Summary

Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular health, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity. Participants will be randomly assigned to either a home-based circuit training group or a control group maintaining usual daily activities. The findings may support the use of home-based exercise as a practical and time-efficient strategy for obesity management and cardiovascular risk reduction.

Conditions

Obesity

Keywords

: circuit training, vascular function, cardiometabolic, physical fitness, obesity

Outcome Measures

Primary Outcomes (1)

• Vascular Function

  Change in flow-mediated dilation from baseline to 12 weeks.

  Baseline and 12 weeks

Study Arms (2)

Home-Based Circuit Training

EXPERIMENTAL

Participants in this group will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit exercise, and cool-down components designed to improve vascular and metabolic health.

Behavioral: Home-Based Circuit Training

Control Group

NO INTERVENTION

participants in the control group will maintain their usual daily activities without participating in the exercise intervention during the study period.

Interventions

Home-Based Circuit Training BEHAVIORAL

Participants will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit-based exercises targeting major muscle groups, and cool-down activities. The intervention is designed to improve vascular and metabolic health in adults with obesity. The training program consisted of two phases: phase 1 (weeks 1-6) and phase 2 (weeks 7-12). During phase 1, participants performed resistance exercises at an intensity of 65-70% of one-repetition maximum (1RM). Each exercise consisted of 12 repetitions, with a 1-minute rest between exercises. The lifting tempo was maintained at 2:2 (concentric: eccentric). Participants completed 8 exercises per circuit for a total of 3 circuits, with a 2-minute rest between circuits. During phase 2, the intensity was increased to 70-75% of 1RM, while maintaining 12 repetitions per exercise. The rest interval between exercises was reduced to 30 seconds, with the same lifting tempo (2:2). Participants complete

Home-Based Circuit Training

Eligibility Criteria

• Age: 19 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Adults with obesity according to the Asia-Pacific criteria (body mass index \[BMI\] ≥ 27.5 kg/m²).
• Able to participate in a home-based exercise program.
• Willing to provide written informed consent.

You may not qualify if:

• History of uncontrolled diabetes (HbA1c ≥ 10% or blood glucose ≥ 200 mg/dL).
• Uncontrolled hypertension (≥ 140/90 mmHg).
• Cardiovascular disease.
• Chronic obstructive pulmonary disease.
• Orthopedic conditions limiting exercise participation.
• Participation in regular exercise programs or sports activities within the previous 3 months

Sponsors & Collaborators

• Chulalongkorn University: lead

Study Sites (1)

Faculty of Sports Science, Chulalongkorn University

Bangkok, ฺBangkok, 10330, Thailand

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Daroonwan Suksom, PhD

  Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand

  STUDY DIRECTOR

• Tunyakarn Worasettawat, PhD

  Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand

  PRINCIPAL INVESTIGATOR

• Hirofumi Tanaka, PhD

  Department of Kinesiology and Health Education, The University of Texas at Austin, USA

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants will be randomly assigned to either a home-based circuit training group or a control group in a parallel-group design.

Study Record Dates

• First Submitted: May 26, 2026
• First Posted: June 2, 2026
• Study Start: June 18, 2025
• Primary Completion: August 31, 2025
• Study Completion: December 25, 2025
• Last Updated: June 2, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)