Exercise Snacks in Obesity

NCT06924346 | Recruiting

• 1 other identifier: H24-OB-snacks
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 2

Brief Summary

To conduct a randomized control trial to determine the feasibility and preliminary efficacy of a 12-week technology-enabled exercise snacks intervention with behaviour change counselling for improving cardiorespiratory fitness and various markers of cardiometabolic health in previously inactive adults living with obesity.

Conditions

Obesity

Outcome Measures

Primary Outcomes (4)

• Determine the number of individuals living with obesity that are eligible to participate in the trial

  The number of participants approached and reasons for not joining the study.

  through study completion, an average of 18 months

• Determine the number of eligible participants who would be willing to take part in this trial

  The number of participants who enroll.

  through study completion, an average of 18 months

• Determine the number and percentage of participants retained after the 12-week intervention

  Number and percentage of participants who drop-out and reasons.

  after the 12-week intervention

• Determine the number of one-minute exercise bouts performed during the 12-week intervention

  Number of exercise bouts performed each week of the intervention.

  during the 12 weeks

Secondary Outcomes (11)

• Change in cardiorespiratory fitness measured before and after the 12-week intervention

  0-12 weeks

• Change in lower body muscular endurance before and after the 12-week intervention

  0-12 weeks

• Change in upper body maximal strength before and after the 12-week intervention

  0-12 weeks

• Change in waist circumference before and after the 12-week intervention

  0-12 weeks

• Change in weight before and after the 12-week intervention

  0-12 weeks

Study Arms (2)

Exercise Snacks

EXPERIMENTAL

Vigorous-intensity bodyweight exercises performed 4 times per day on at least 5 days per week.

Other: Exercise Snacks

Placebo Exercise

ACTIVE COMPARATOR

Low-intensity stretching exercises performed 4 times per day on at least 5 days per week.

Other: Placebo Exercise

Interventions

Exercise Snacks OTHER

The "movement breaks" will be individualized to exercise preferences and physical abilities (e.g., fitness, musculoskeletal issues) and adaptable to multiple environments (e.g., home, work) delivered via mobile phone application. Participants will be encouraged to incorporate the movement breaks into their daily schedule based on baseline exercise counselling.

Exercise Snacks

Placebo Exercise OTHER

The "movement breaks" will be individualized to exercise preferences and physical abilities (e.g., fitness, musculoskeletal issues) and adaptable to multiple environments (e.g., home, work) delivered via mobile phone application. Participants will be encouraged to incorporate the movement breaks into their daily schedule based on baseline exercise counselling.

Placebo Exercise

Eligibility Criteria

• Age: 35 Years - 64 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Aged 35-64 years.
• Habitually engaging in \< 150 min moderate-to-vigorous physical activity per week.
• Body mass index 30-45 kg/m2 or 27.5-45 for participants who self-identify as being of Asian or Southeast Asian origin.
• Waist circumference: \>88cm for females and \>102cm for males, or \>80 cm for females and \>90 cm for male participants who self-identify as being of Asian or Southeast Asian.
• Not currently diagnosed with a cardiometabolic disease (e.g., coronary artery disease, stroke, diabetes, non-alcoholic fatty liver disease).
• Taking ≤2 commonly prescribed medications for the prevention of cardiometabolic diseases (e.g., statins, antihypertensives).
• Not a current smoker
• Cleared to engage in physical activity using the Get Active Questionnaire and, if applicable, consultation with a health care provider or Qualified Exercise Professional.
• Access to a computer, tablet or smartphone for intervention delivery and tracking.
• Ability to read and write in English.

You may not qualify if:

• Chronic musculoskeletal condition or recent (within 2 years) cardiovascular event preventing participation in exercise.
• Lack of internet access.
• Angina upon exertion assessed by the Rose Angina Questionnaire.
• Prescribed beta-blockers that can compromise the validity of heart rate measurements. during the exercise test.
• Have a scheduled surgical procedure within the next 3-4 months that would prevent exercise participation.
• Currently participating in another clinical trial that interferes with the study procedures.
• Currently pregnant or planning on becoming pregnant during the intervention (i.e., within the next 4 months).
• Uncontrolled high blood pressure (\>160/90 mmHg)

Sponsors & Collaborators

• University of British Columbia: lead
• McMaster University: collaborator

Study Sites (2)

University of British Columbia Okanagan

Kelowna, British Columbia, Canada

RECRUITING

McMaster University

Hamilton, Ontario, Canada

RECRUITING

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Jonathan P Little, PhD

CONTACT

250-807-9876; jonathan.little@ubc.ca

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: March 26, 2025
• First Posted: April 11, 2025
• Study Start: July 14, 2025
• Primary Completion: May 1, 2026
• Study Completion: May 1, 2026
• Last Updated: April 2, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

CA (2)