Delphi Septic Shock: Sub-phenotypes Using Point-of-Care Ultrasound in Patients With Septic Shock

NCT07616817 | Enrolling By Invitation

• 1 other identifier: 7146
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The Delphi survey process is a well-established mechanism for generating consensus on a certain topic by using a panel "collective intelligence". The Steering Committee, made up of critical care physicians, will undertake a literature search on available information, including existing hemodynamic sub-phenotypes and the use of point-of-care ultrasound in the classification and management of septic shock. The Steering Committee will not participate in the Delphi surveys. The anonymity of the Experts will be maintained until the end of the Delphi rounds. Point-of-care ultrasound has been proposed as a quick bed-side tool to identify hemodynamic subphenotypes and may guide personalized management. However, there is a dearth of evidence supporting the presence of these subphenotypes and management recommendations (if any) based on these subphenotypes. Thus, the objective of this study would be to conduct a survey, using the Delphi method, to obtain a consensus from critical care experts on classification and management of hemodynamic cardiac and lung phenotypes.

Conditions

Septic Shock; Sepsis; Shock

Keywords

point-of-care ultrasound; delphi; hemodynamic management; echo phenotypes; septic shock; consensus; ultrasound; anesthesiology; critical care

Outcome Measures

Primary Outcomes (1)

• Percentage of agreement on statements in Delphi rounds on the classification of hemodynamic sub-phenotypes using point-of-care ultrasound in patients with septic shock.

  To generate consensus position statements on the classification of hemodynamic sub-phenotypes using point-of-care ultrasound and clinical assessment of patients with septic shock--based on percentage of agreement of the statements.

  through study completion, on average, 6 months.

Secondary Outcomes (1)

• Percentage of agreement on statements in Delphi rounds on the management of hemodynamic sub-phenotypes using point-of-care ultrasound in patients with septic shock.

  through study completion, on average, 6 months.

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Steering Committee A world-wide Steering Committee (SC) comprised of critical care physicians with expertise in point-of-care ultrasound was formed including one Delphi methodologist. Selection of Experts Healthcare professionals with at least 30% of the clinical work commitment to managing critically ill patients.

You may qualify if:

• Healthcare professionals with at least 30% of the clinical work commitment to managing critically ill patients.
• AND at least one of the following:
• At least one publication on point-of-care ultrasound in critically ill patients
• Accreditation/certification/ institutional credentialing in point-of-care ultrasound or echocardiography.
• Ten or more years of experience in point-of-care ultrasonography in critically ill patients. 35-50 International experts from six continents will be engaged in the Delphi process.
• Concerted efforts will be made to ensure that at least 50% of the experts are from low-and middle-income countries and not more than 70% are from each sex.

Sponsors & Collaborators

• Albany Medical College: lead

Study Sites (1)

Albany Medical College

Albany, New York, 12208, United States

Location

Related Links

• Perioperative Management of Patients with Sepsis and Septic Shock, Part II: Ultrasound Support for Resuscitation.
• Delphi methodology in healthcare research: How to decide its appropriateness

MeSH Terms

Conditions

Shock, Septic; Sepsis; Shock

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiology & Critical Care Professor and Vice Chair of Education

Study Record Dates

• First Submitted: May 19, 2026
• First Posted: June 1, 2026
• Study Start: December 5, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 1, 2027
• Last Updated: June 1, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)