NCT07616804

Brief Summary

This study aims to investigate the acute cognitive and physiological responses to breath-hold diving training in trained female divers. Participants will complete three separate sessions including a control session, a land-based breath-hold training session, and a water-based breath-hold training session in randomized order. Cognitive performance, mood state, heart rate responses, respiratory function, and maximal breath-hold capacity will be evaluated before and after the interventions. The study is expected to improve understanding of how acute apnea-based diving exercises influence cognitive functions and physiological adaptations under different environmental conditions.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
2mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress58%
Jun 2026Sep 2026

First Submitted

Initial submission to the registry

May 7, 2026

Completed
25 days until next milestone

First Posted

Study publicly available on registry

June 1, 2026

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2026

Expected
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2026

Last Updated

June 1, 2026

Status Verified

May 1, 2026

Enrollment Period

3 months

First QC Date

May 7, 2026

Last Update Submit

May 27, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Working Memory Accuracy (2-Back Test)

    Accuracy score obtained from the computerized 2-back cognitive task.

    Baseline and immediately after the intervention, within 5 minutes post-intervention.

  • Reaction Time During the 2-Back Test

    Mean reaction time recorded during correct responses in the 2-back cognitive task.

    Baseline and immediately after the intervention, within 5 minutes post-intervention.

Secondary Outcomes (4)

  • Brunel Mood Scale (BRUMS) Total Score

    Baseline and immediately after the intervention, within 5 minutes post-intervention.

  • Maximum Breath-Hold Duration

    Baseline during the control session before intervention sessions.

  • Resting Heart Rate

    Before each experimental session.

  • Exercise Heart Rate Response

    During the intervention session.

Study Arms (3)

Control Session

EXPERIMENTAL

Participants will complete baseline cognitive, respiratory, mood, and maximal breath-hold assessments without structured breath-hold exercise.

Other: Control Session

Land-Based Breath-Hold Training

EXPERIMENTAL

Participants will perform land-based breath-hold exercises at 60% of individual maximal breath-hold capacity followed by post-intervention cognitive and mood assessments.

Behavioral: Land-Based Breath-Hold Training

Water-Based Breath-Hold Training

EXPERIMENTAL

Participants will perform water-based breath-hold exercises in a swimming pool at 60% of individual maximal breath-hold capacity followed by post-intervention cognitive and mood assessments.

Behavioral: Water-Based Breath-Hold Training

Interventions

Participants will perform structured land-based breath-hold exercises consisting of repeated apnea efforts at 60% of individual maximal breath-hold capacity with standardized rest intervals.

Land-Based Breath-Hold Training

Participants will perform structured breath-hold exercises in a swimming pool environment consisting of repeated apnea efforts at 60% of individual maximal breath-hold capacity with standardized rest intervals.

Water-Based Breath-Hold Training

Participants will undergo baseline cognitive, respiratory, mood, and physiological assessments without structured apnea or breath-hold exercise intervention.

Control Session

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Licensed breath-hold or free-diving athletes
  • Aged between 18 and 30 years
  • Minimum of 5 years of training experience
  • No known cardiovascular or pulmonary disease
  • Non-smokers
  • Willing to participate voluntarily
  • Refraining from intense exercise within 24 hours before testing

You may not qualify if:

  • Use of performance-enhancing drugs or ergogenic aids
  • Presence of chronic sports injury
  • Alcohol consumption within 24 hours before testing
  • Caffeine intake within 2 hours before testing
  • Sleep deprivation or severe fatigue
  • Current medication use Fear of water or inability to complete breath-hold procedures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Gelisim University

Istanbul, 34000, Turkey (Türkiye)

Location

Central Study Contacts

Görkem Açar, Ress. Asst.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
No masking procedures will be applied because participants and investigators will be aware of the intervention conditions during the sessions.
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Model Details: Participants will complete control, land-based breath-hold, and water-based breath-hold sessions in randomized crossover order. Cognitive, physiological, and mood-related responses will be evaluated before and after each session.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ress. Asst.

Study Record Dates

First Submitted

May 7, 2026

First Posted

June 1, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

August 30, 2026

Study Completion (Estimated)

September 15, 2026

Last Updated

June 1, 2026

Record last verified: 2026-05

Locations