Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults

NCT07614464 | Recruiting

• 1 other identifier: 01C514
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people. To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.

Conditions

Obesity; Sarcopenic Obesity

Keywords

Ageing; Obesity; Physical performance; Visceral adiposity

Outcome Measures

Primary Outcomes (4)

• Fat mass

  Fat mass as assessed by bioelectrical impedance

  Baseline

• Lean mass

  Lean mass as assessed by bioelectrical impedance

  Baseline

• Barthel Index

  Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100

  Baseline

• Handgrip test

  Score in kilograms (kg) using a hand dynamometer

  Baseline

Study Arms (2)

Obese elderly

Obese men and women of 65 years and older

Other: Fitness tests and questionnaires

Normal weight elderly

Normal weight men and women of 65 years and older

Other: Fitness tests and questionnaires

Interventions

Fitness tests and questionnaires OTHER

Anthropometric measurements, physical fitness tests and daily life questionnaires

Normal weight elderly; Obese elderly

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hospitalized obese elderly following a 3-week integrated metabolic rehabilitation program \+ Normal weight elderly attending correct lifestyle program in their home town

You may qualify if:

• Both sexes
• Body Mass Index \> 35 kg/m2
• Age \> 65 years
• Hospitalized for a 3-week integrated metabolic rehabilitation program

You may not qualify if:

• Absence of signed informed consent
• Normal weight elderly:
• Both sexes
• Body Mass Index 20-25 kg/m2
• Age \> 65 years
• Attendance of healthy lifestyle program in their home town
• Absence of signed informed consent

Sponsors & Collaborators

• Istituto Auxologico Italiano: lead

Study Sites (1)

Istituto Auxologico Italiano IRCCS, Site Piancavallo

Oggebbio, 28824, Italy

RECRUITING

MeSH Terms

Conditions

Obesity

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

Alessandro Sartorio, MD

CONTACT

+3902619111; sartorio@auxologico.it

Luca Grappiolo, Dr

CONTACT

+3902619111; luca.grappiolo@auxologico.it

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 22, 2026
• First Posted: May 29, 2026
• Study Start: May 29, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: May 29, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)