Effects of Concurrent Training on Physical Fitness and Body Composition in Obese Individuals

NCT05768581 | Completed

• 1 other identifier: 43C202
• Study Type: interventional
• Target: 132
• Locations: 1 country
• Sites: 1

Brief Summary

Ample evidence demonstrates the beneficial role of physical activity combined with a structured dietary plan to counteract obesity. International guidelines as the World Health Organization states that to improve fitness levels at least 150 min a week of physical activity at moderate intensity, combined with resistance training composed of 8-12 repetitions with an intensity of 60-70%1RM for each muscle group, are recommended. In this regard, a minimum dosage of 60-90 min of physical activity composed by aerobic exercises in alternation with resistance training protocols, allow a sequential development of cardiorespiratory fitness and muscular strength parameters avoiding potential interference effects. Interference may occur when strength and endurance stimuli both target opposite peripheral adaptations (e.g., hypertrophy vs. muscle capillarization) and this phenomenon seems to be particularly clear during adolescence. Nevertheless, the incorporation of different training stimuli within the same training session is called Concurrent Training. This training mode, thanks to the activation of two different metabolic pathways (e.g., aerobic and anaerobic), has a variety, beneficial effects in terms of muscle mass and strength development, body composition profile regulation and neuromotor function improvement. Concurrent Training seems to be effective not only in normal-weight subjects, but also in obese individuals, reporting positive adaptations on physical fitness and health status compared with a single-mode (i.e., aerobic or strength training). Therefore, the aim of this study is to detect the effects of a 10-week-Concurrent Training protocol compared with a single training modality on physical fitness, body composition and circadian rhythms in adult outpatients with obesity.

Conditions

Obesity

Keywords

physical activity; obesity treatment; body composition

Outcome Measures

Primary Outcomes (3)

• Change from baseline strength in kilograms at 10 weeks

  Maximum isometric handgrip strength using a dynamometer

  Up to 10 weeks

• Change from baseline cardiorespiratory fitness in number of steps performed at 10 weeks fitness

  Maximum aerobic capacity using the two minute step test

  Up to 10 weeks

• Change from baseline postural control in arbitrary units at 10 weeks

  Balance and postural control using the Balance Error Scoring System

  Up to 10 weeks

Secondary Outcomes (5)

• Change from baseline fat mass percentage at 10 weeks

  Up to 10 weeks

• Change from baseline weight in kilograms at 10 weeks

  Up to 10 weeks

• Change from baseline height in meters at 10 weeks

  Up to 10 weeks

• Change from baseline waist circumference in centimeters at 10 weeks

  Up to 10 weeks

• Change from baseline circadian rhythm in arbitrary units at 10 weeks

  Up to 10 weeks

Study Arms (3)

Concurrent Training

EXPERIMENTAL

Experimental: home-based concurrent training composed by strength and aerobic exercises within the same training session

Other: Concurrent Training

Strength Training

EXPERIMENTAL

Experimental: home-based resistance training mode

Other: Strength Training

Aerobic Training

EXPERIMENTAL

Experimental: home-based endurance training mode

Other: Aerobic training

Interventions

Concurrent Training OTHER

Participants should perform strength training and aerobic exercises

Concurrent Training

Strength Training OTHER

Participants should perform strength exercises

Strength Training

Aerobic training OTHER

Participants should perform aerobic exercises

Aerobic Training

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Physical activity frequency minor of 2 days/week
• BMI major of 30 kg/m2
• informed consent signature

You may not qualify if:

• age over 65 years
• knee or hip pain (visual analogue scale score \>7 arbitrary units
• a history of hip, knee or foot replacement or osteoarthrosis
• cardiac infarction
• neurological impairments or any other clinical condition that affects the practice of physical activity

Sponsors & Collaborators

• Istituto Auxologico Italiano: lead

Study Sites (1)

Istituto Auxologico Italiano IRCCS

Milan, 20145, Italy

Location

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MeSH Terms

Conditions

Obesity; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 20, 2023
• First Posted: March 14, 2023
• Study Start: October 1, 2022
• Primary Completion: February 28, 2023
• Study Completion: April 30, 2024
• Last Updated: August 21, 2025

Record last verified: 2025-08

Locations

IT (1)