NCT07610200

Brief Summary

This randomized controlled study aims to investigate the effects of myofascial release therapy on body posture and facial symmetry in healthy individuals. Postural disorders and fascial tension may lead to biomechanical alterations not only in the musculoskeletal system but also in facial soft tissues and symmetry. Myofascial release techniques are widely used in physiotherapy to improve fascial mobility, reduce tissue tension, and support postural alignment. However, the potential effects of these interventions on facial symmetry have not been sufficiently investigated. A total of 60 healthy participants will be included in the study and randomly assigned to either an intervention group or a control group. Participants in the intervention group will receive myofascial release therapy twice weekly for 6 weeks, while the control group will not receive any physical intervention during the same period. Body posture and facial symmetry assessments will be performed at baseline and after the intervention period. Postural assessment will be conducted using the PostureScreen Mobile application through standardized anterior, posterior, and lateral photographs. Facial symmetry will be evaluated using anthropometric facial landmarks identified on standardized facial photographs. Directional asymmetry scores, linear measurements, proportional analyses, and angular measurements will be calculated. The study is expected to provide evidence regarding the relationship between fascial interventions, postural alignment, and facial symmetry, and may contribute to the development of new physiotherapy approaches targeting fascial and postural dysfunctions.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
18mo left

Started Jun 2026

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 27, 2026

Completed
19 days until next milestone

Study Start

First participant enrolled

June 15, 2026

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2027

Expected
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

May 27, 2026

Status Verified

May 1, 2026

Enrollment Period

8 months

First QC Date

May 20, 2026

Last Update Submit

May 20, 2026

Conditions

Keywords

Myofascial Release TherapyPostureFacial SymmetryFascial SystemManual TherapyPostural AlignmentPhysiotherapyFacial AsymmetryMyofascial DysfunctionRandomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

  • Change in Facial Directional Asymmetry Score

    Facial symmetry will be evaluated using standardized digital facial photographs and anthropometric facial landmarks. Directional asymmetry scores will be calculated by comparing right and left facial measurements before and after the intervention period.

    Baseline and after 6 weeks of intervention

Study Arms (2)

Myofascial Release Therapy Group

EXPERIMENTAL

Participants in this group will receive myofascial release therapy twice weekly for 6 weeks. The intervention protocol will include cervical, thoracic, shoulder, and fascial manual therapy techniques performed by a trained physiotherapist.

Procedure: Myofascial Release Therapy

Control Group

NO INTERVENTION

Participants in the control group will not receive any manual therapy or physical intervention during the study period and will only undergo assessment procedures.

Interventions

Participants assigned to the intervention group will receive standardized myofascial release therapy performed by a trained physiotherapist twice weekly for 6 weeks. The intervention protocol will include single arm pull, lateral neck shoulder release, thoracic transverse plane technique, and anterior cervical fascial release techniques targeting cervical, thoracic, shoulder, and fascial regions. Each session will be conducted under standardized clinical conditions to improve fascial mobility, reduce tissue tension, and support postural alignment and facial symmetry.

Also known as: Myofascial Therapy, Fascial Release Therapy, Manual Myofascial Release
Myofascial Release Therapy Group

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy individuals aged between 18 and 45 years
  • Ability to understand and follow study instructions
  • Independent performance of daily living activities
  • No regular physiotherapy or manual therapy treatment within the previous 3 months
  • Willingness to participate voluntarily and sign the informed consent form
  • Ability to attend assessment and intervention sessions regularly

You may not qualify if:

  • History of neurological or orthopedic disorders affecting posture or facial symmetry
  • Current musculoskeletal injury or ongoing rehabilitation treatment
  • Previous facial, spinal, or major musculoskeletal surgery or trauma
  • Pregnancy
  • Use of medications affecting muscle tone or neuromuscular function
  • Psychiatric or cognitive disorders limiting study participation
  • Inability to comply with study procedures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Szucs KA, Brown EVD. Rater reliability and construct validity of a mobile application for posture analysis. J Phys Ther Sci. 2018 Jan;30(1):31-36. doi: 10.1589/jpts.30.31. Epub 2018 Jan 27.

    PMID: 29410561BACKGROUND
  • Wilke J, Krause F, Vogt L, Banzer W. What Is Evidence-Based About Myofascial Chains: A Systematic Review. Arch Phys Med Rehabil. 2016 Mar;97(3):454-61. doi: 10.1016/j.apmr.2015.07.023. Epub 2015 Aug 14.

    PMID: 26281953BACKGROUND
  • Schleip R, Jager H, Klingler W. What is 'fascia'? A review of different nomenclatures. J Bodyw Mov Ther. 2012 Oct;16(4):496-502. doi: 10.1016/j.jbmt.2012.08.001. Epub 2012 Aug 22.

    PMID: 23036881BACKGROUND

MeSH Terms

Conditions

Facial Asymmetry

Interventions

Myofascial Release Therapy

Condition Hierarchy (Ancestors)

Pathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

MassageTherapy, Soft TissueMusculoskeletal ManipulationsComplementary TherapiesTherapeuticsPhysical Therapy ModalitiesRehabilitation

Study Officials

  • Ece Acar

    Karabuk University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ece Acar, Assistant Professor, Physiothe

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcome assessors analyzing posture photographs and facial symmetry measurements will be blinded to group allocation. Participants and therapists providing the intervention will not be blinded due to the nature of the manual therapy application.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned to either the intervention group or the control group using a parallel-group design. The intervention group will receive myofascial release therapy twice weekly for 6 weeks, while the control group will undergo observation and assessment only. Outcome assessments will be performed at baseline and after completion of the intervention period.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor, Department of Physiotherapy and Rehabilitation

Study Record Dates

First Submitted

May 20, 2026

First Posted

May 27, 2026

Study Start

June 15, 2026

Primary Completion (Estimated)

February 1, 2027

Study Completion (Estimated)

December 1, 2027

Last Updated

May 27, 2026

Record last verified: 2026-05