Bilateral Erector Spinae Plane Block Versus Bilateral Oblique Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia in Colorectal Surgery

NCT07602452 | Recruiting

• 1 other identifier: MD-316-2026
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the ultrasound-guided bilateral erector spinae plane block (ESPB) and oblique subcostal transverse abdominal plane block (OSTAPB) for postoperative analgesia in colorectal surgery.

Conditions

Bilateral Erector Spinae Plane Block; Postoperative Analgesia; Colorectal Surgery; Bilateral Oblique Subcostal Transversus Abdominis Plane Block

Outcome Measures

Primary Outcomes (1)

• Degree of pain

  Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS). NRS (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS will be assessed at 0, 2, 4, 6, 12, and 24 h postoperatively.

  24 hours postoperatively

Secondary Outcomes (8)

• Time to the first rescue analgesia

  24 hours postoperatively

• Intraoperative fentanyl consumption

  Intraoperatively

• Total morphine consumption

  24 hours postoperatively

• Mean arterial pressure

  Till end of surgery (Up to 2 hours)

• Heart rate

  Till end of surgery (Up to 2 hours)

Study Arms (2)

Group I

EXPERIMENTAL

Patients will receive ultrasound-guided erector spinae plane block.

Other: Erector Spinae Plane Block

Group II

EXPERIMENTAL

Patients will receive ultrasound-guided oblique subcostal transversus abdominis plane block.

Other: Oblique Subcostal Transversus Abdominis Plane Block

Interventions

Erector Spinae Plane Block OTHER

Patients will receive ultrasound-guided erector spinae plane block.

Group I

Oblique Subcostal Transversus Abdominis Plane Block OTHER

Patients will receive ultrasound-guided oblique subcostal transversus abdominis plane block.

Group II

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 to 75 years old.
• Both sexes.
• American Society of Anesthesiologists (ASA) physical status II-III.
• Scheduled for open colorectal surgery under general anesthesia.

You may not qualify if:

• History of opioid abuse.
• Chronic opioid consumption.
• Body mass index (BMI) ≥ 35 kg/m2.
• Severe cardiac insufficiency, defined as New York Heart Association (NYHA) class III or IV heart failure.
• Renal failure, defined as an estimated glomerular filtration rate (eGFR) \< 30 mL/min/1.73 m².
• Hepatic encephalopathy.
• Having a skin infection at or near the puncture site.
• Coagulopathy, defined as platelet count \< 100,000/mm³, INR \> 1.5, or use of anticoagulant therapy that could not be withheld.
• Allergy to drugs used in the study.
• History of previous or recurrent laparoscopic cholecystectomy procedures.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

RECRUITING

Central Study Contacts

Mohammed M Alarousy, MSc

CONTACT

00201149404478; mohammedalarousy0@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Management, Cairo University, Tanta, Egypt.

Study Record Dates

• First Submitted: May 16, 2026
• First Posted: May 22, 2026
• Study Start: May 21, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: May 22, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)