NCT07599241

Brief Summary

additive efficacy of physical activity program in hypthyroidism in elder females with glaucoma and fatty liver issues was not investigated

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
7mo left

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress25%
Mar 2026Dec 2026

Study Start

First participant enrolled

March 15, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 9, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

May 20, 2026

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2026

Last Updated

May 20, 2026

Status Verified

May 1, 2026

Enrollment Period

9 months

First QC Date

May 9, 2026

Last Update Submit

May 14, 2026

Conditions

Subclinical hypothyroïdismNon-Alcoholic Fatty Liver DiseasePrimary Open Angle Glaucoma

Outcome Measures

Primary Outcomes (1)

  • intraocular pressure

    it will be assessed in both eyes

    6 months

Secondary Outcomes (13)

  • body mass index

    6 months

  • waist circumfrence

    6 months

  • systolic blood pressure

    6 months

  • diastolic blood pressure

    6 months

  • glaucoma assocaited life quality survey

    6 months

  • +8 more secondary outcomes

Study Arms (2)

group number 1

EXPERIMENTAL

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues recive their levothyroxine and physical activity program on treadmill thrice weekly for 6 month

Behavioral: physical activity

group number 2

ACTIVE COMPARATOR

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues will recive their levothyroxine only

Other: usual care

Interventions

physical activityBEHAVIORAL

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine and physical activity program on treadmill thrice weehly for 6 month

group number 1
usual careOTHER

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine only

group number 2

Eligibility Criteria

Age65 Years - 75 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsbased on self-representation of gender identity.
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • subclinical hypothrodism (significant form)
  • primary opened angle gaulcoma in both eyes with ocular hypertension in both eyes )(high-tension typed glaucoma)
  • fatty liver (non alcholic type)
  • elder females

You may not qualify if:

  • respiratory issues
  • cardiac issues
  • renal issues

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Dokki, Giza Governorate, 11432, Egypt

RECRUITING

MeSH Terms

Conditions

Non-alcoholic Fatty Liver DiseaseGlaucoma, Open-Angle

Interventions

Exercise

Condition Hierarchy (Ancestors)

Fatty LiverLiver DiseasesDigestive System DiseasesGlaucomaOcular HypertensionEye Diseases

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Ali MA Ismail, lecturer

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ali MA Ismail, lecturer

CONTACT

01005154209ali.mohamed@pt.cu.edu.eg

fatma M Ali

CONTACT

01031321109fatma1995@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

Study Record Dates

First Submitted

May 9, 2026

First Posted

May 20, 2026

Study Start

March 15, 2026

Primary Completion (Estimated)

December 15, 2026

Study Completion (Estimated)

December 15, 2026

Last Updated

May 20, 2026

Record last verified: 2026-05

Locations

EG(1)