Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

63 trials with published results (11%)

Research Maturity

292 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.6%

26 terminated out of 568 trials

Success Rate

91.8%

+5.3% vs benchmark

Late-Stage Pipeline

9%

51 trials in Phase 3/4

Results Transparency

22%

63 of 292 completed with results

Key Signals

63 with results92% success26 terminated

Data Visualizations

Phase Distribution

408Total
Not Applicable (230)
Early P 1 (5)
P 1 (49)
P 2 (73)
P 3 (15)
P 4 (36)

Trial Status

Completed292
Unknown117
Recruiting75
Active Not Recruiting26
Terminated26
Not Yet Recruiting13

Trial Success Rate

91.8%

Benchmark: 86.5%

Based on 292 completed trials

Clinical Trials (568)

Showing 20 of 20 trials
NCT06374875Phase 4Recruiting

Fibrosis Lessens After Metabolic Surgery

NCT07740109Not ApplicableNot Yet RecruitingPrimary

The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

NCT07093346Not ApplicableRecruitingPrimary

The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT02863757Recruiting

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

NCT03190538RecruitingPrimary

Nonalcoholic Steatohepatitis in Chinese Children

NCT07221227Phase 3RecruitingPrimary

A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

NCT05268042Not ApplicableCompletedPrimary

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT07221188Phase 3RecruitingPrimary

A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

NCT07335198Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of Efimosfermin Alfa Administered as a Single Dose to Healthy Participants of Chinese, Japanese, and White/European Ancestry

NCT04785937Not ApplicableCompletedPrimary

Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients

NCT03884075Phase 2Recruiting

Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

NCT00230087Not ApplicableCompletedPrimary

Iron Depletion Therapy for Type 2 DM and NAFLD

NCT00230113Not ApplicableCompletedPrimary

Effect of Omega-3 PUFA Supplementation in NAFLD Patients

NCT06005012Phase 2Active Not Recruiting

Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM

NCT07644936Not Yet Recruiting

Molecular Characterization of Autoimmune Hepatitis: A Lipidomic Approach

NCT04302051Withdrawn

Assessment of Fatty Liver With Thermo-acoustic Device

NCT06920043Phase 2Recruiting

A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

NCT07403604Phase 1Recruiting

Effect of Insulin Lowering on Lipogenesis

NCT02506946Suspended

NAFLD in Adolescents and Young Adults With PCOS

NCT05583344Phase 2Active Not Recruiting

Phase 2b Study of GSK4532990 in Adults With NASH

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