Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

63 trials with published results (11%)

Research Maturity

290 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

4.6%

26 terminated out of 566 trials

Success Rate

91.8%

+5.3% vs benchmark

Late-Stage Pipeline

9%

51 trials in Phase 3/4

Results Transparency

22%

63 of 290 completed with results

Key Signals

63 with results92% success26 terminated

Data Visualizations

Phase Distribution

406Total
Not Applicable (227)
Early P 1 (5)
P 1 (49)
P 2 (74)
P 3 (15)
P 4 (36)

Trial Status

Completed290
Unknown118
Recruiting76
Terminated26
Active Not Recruiting25
Not Yet Recruiting12

Trial Success Rate

91.8%

Benchmark: 86.5%

Based on 290 completed trials

Clinical Trials (566)

Showing 20 of 20 trials
NCT07644936Not Yet Recruiting

Molecular Characterization of Autoimmune Hepatitis: A Lipidomic Approach

NCT05890365RecruitingPrimary

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

NCT07358546Phase 1RecruitingPrimary

A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

NCT04141592RecruitingPrimary

Investigating Pathological Mechanisms in Non-alcoholic Fatty Liver Disease

NCT05330923RecruitingPrimary

Screening and Follow-up in Patients With HIV Infection Combined With Metabolic Associated Fatty Liver Disease

NCT05292352Not ApplicableTerminatedPrimary

Prevention of NAFLD in Hispanic Children

NCT06482112Phase 2Completed

Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)

NCT05268042Not ApplicableActive Not RecruitingPrimary

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT06944353Not ApplicableEnrolling By InvitationPrimary

Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED

NCT06819917Recruiting

Identification of Liver Fibrosis Biomarkers

NCT04951219Phase 3Active Not RecruitingPrimary

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

NCT05583344Phase 2Active Not Recruiting

Phase 2b Study of GSK4532990 in Adults With NASH

NCT07599241Not ApplicableRecruiting

Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues

NCT04801849Phase 2CompletedPrimary

Vitamin E Dosing Study

NCT03884075Phase 2Recruiting

Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)

NCT06240039Not ApplicableActive Not RecruitingPrimary

Direct Versus Indirect Effect of Amino Acids on Hepatokines

NCT06053177Active Not Recruiting

Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes

NCT07570810Not ApplicableNot Yet Recruiting

Efficacy, Safety, and Tolerability of CS0159 Combined With Semaglutide in MAFLD Patients With Obesity and T2DM

NCT06863376Phase 2RecruitingPrimary

Evaluating the Safety and Efficacy of Carbocisteine in the Treatment of Nonalcoholic Fatty Liver Disease Patients

NCT05180760Not ApplicableActive Not RecruitingPrimary

Smartphone App for Non-alcoholic Fatty Liver Disease

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