Evaluation of Low Energy Level Laser Biostimulation at Different Energy Densities in the Treatment of Temporomandibular Joint Irregularities: A Retrospective Study

NCT07588841 | Completed

• 1 other identifier: 64529847/7
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical study aimed to evaluate the effectiveness of low-level laser therapy in patients with temporomandibular disorders (TMD), specifically disc displacement with reduction and myalgia. The study compared laser therapy with a soft diet approach to determine whether laser treatment provides additional benefits in reducing pain and improving jaw function

Conditions

Myalgia of Mastication Muscle

Outcome Measures

Primary Outcomes (1)

• Change in temporomandibular pain intensity measured by the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up

  Change in temporomandibular pain intensity was assessed using the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up. The Visual Analog Scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Higher scores represent greater pain severity.

  6 month

Study Arms (2)

Low Level Laser Therapy

ACTIVE COMPARATOR

Participants in this group received low-level laser therapy applied to the temporomandibular joint region according to the predefined treatment protocol. Laser therapy was administered for 2 minutes per joint over 9 treatment sessions. Patients were also advised to follow a soft diet during the treatment period.

Other: Low Level Laser Therapy

soft diet group

OTHER

Soft Diet Group: Participants in this group did not receive laser therapy and were instructed to follow a soft diet during the study period. This group served as the comparison group for evaluating treatment outcomes.

Other: Dietary Supplement

Interventions

Low Level Laser Therapy OTHER

Participants received low-level laser therapy applied to the temporomandibular joint region in addition to soft diet recommendations. Treatment was performed in 9 sessions according to the predefined laser protocol. Participants followed a soft diet regimen without receiving laser therapy and served as the comparison group.

Low Level Laser Therapy

Dietary Supplement OTHER

Participants in this group did not receive laser therapy and were instructed to follow a soft diet during the study period. This group served as the comparison group for evaluating treatment outcomes.

soft diet group

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of disc displacement with reduction (DDwR) and myalgia according to DC/TMD criteria Presence of temporomandibular joint pain and functional limitation Patients aged 18 years and older No previous temporomandibular joint (TMJ) treatment Absence of systemic diseases Willingness to participate and provide informed consent

You may not qualify if:

• History of previous TMJ treatment (e.g., conservative or surgical treatment) Congenital or inflammatory joint disease Severe systemic diseases Edentulous patients Children and adolescents in the active growth period Acute trauma history involving the TMJ region Inability or unwillingness to complete follow-up visits

Sponsors & Collaborators

• Karadeniz Technical University: lead

Study Sites (1)

Karadeniz Technical University

Trabzon, Trabzon, 61000, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Low-Level Light Therapy; Dietary Supplements

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Participants were assigned to one of two parallel groups: a low-level laser therapy group or a soft diet group. Outcomes were assessed at baseline, after completion of treatment sessions, and during follow-up evaluations.

Study Record Dates

• First Submitted: May 7, 2026
• First Posted: May 15, 2026
• Study Start: September 3, 2022
• Primary Completion: December 24, 2024
• Study Completion: December 24, 2024
• Last Updated: May 15, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)