The Effect of Low Level Laser Therapy on Improvement of Temporomandibular Joint Osteoarthritis

NCT01417650 | Unknown DMC

• 1 other identifier: 89342
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Temporomandibular disorder (TMD) is the major cause of nondental pain in orofacial area. Laser therapy can be considered as one of the most popular methods of pain relief in TMD patients. The special features of laser light such as coherence, monochromaticity, and collimation can result in the ability of laser light to modify cellular metabolism, increase tissue repair and reduce edema and inflammation. The effectiveness of low level laser therapy in reducing the signs and symptoms of temporomandibular joint disorders has been investigated in a few studies. But, in most of the previous studies the etiology of TMD has not been considered in patient selection. Furthermore, there are some controversies in the results of these studies. According to our data, there is no study evaluating the effects of low level laser therapy on patients having TMJ osteoarthritis. The aim of this study is to evaluate the effectiveness of low level laser therapy in improving osteoarthritis of temporomandibular joint and also to evaluate the long term effects of laser therapy on the morphology of the joint.

Conditions

Temporomandibular Joint Disorder

Keywords

temporomandibular disorder; laser therapy; osteoarthritis

Outcome Measures

Primary Outcomes (1)

• Pain relief

  Pain is assessed by visual analogue scale (VAS)

  Up to 1 month after laser theray

Secondary Outcomes (2)

• TMD sounds

  Up to 1 month after laser therapy

• Mouth opening measurement

  Up to 1 month after laser therapy

Study Arms (2)

laser

ACTIVE COMPARATOR

In this group, the 890 nm diode laser (Mustang 2000+,Russia) will be used with frequency of 1500 Hz, and dose of 2 J/cm2 per point in the joint area and painful muscles if any.

Radiation: Low level laser therapy

placebo

PLACEBO COMPARATOR

In this group the low power laser will be applied with minimal dose that is very lower than the threshold necessary for therapeutic effects.

Radiation: Low level laser therapy

Interventions

Low level laser therapy RADIATION

In this group, the 890 nm diode laser (Mustang 2000+, Russia) will be applied with frequency of 1500 Hz, and dose of 2 J/cm2 per point in the joint area and painful muscles if any.

Also known as: low power laser, laser therapy, diode laser

laser

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• The patients are selected according to the RDC/TMD criteria to include those having temporomandibular osteoarthritis with unknown etiology.

You may not qualify if:

• Patients with systemic problems.
• Patients using analgesic or antidepressant drugs.
• Patients undergoing any treatment modality for TMD disease.

Sponsors & Collaborators

• Mashhad University of Medical Sciences: lead

MeSH Terms

Conditions

Temporomandibular Joint Disorders; Osteoarthritis

Interventions

Low-Level Light Therapy; Laser Therapy; Lasers, Semiconductor

Condition Hierarchy (Ancestors)

Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Stomatognathic Diseases; Arthritis; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Therapeutics; Phototherapy; Ablation Techniques; Surgical Procedures, Operative; Lasers; Optical Devices; Equipment and Supplies; Radiation Equipment and Supplies

Study Officials

• Farzaneh Ahrari, DDS, MS

  Mashhad University of Medical Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 8, 2011
• First Posted: August 16, 2011
• Study Start: January 1, 2011
• Primary Completion: October 1, 2011
• Study Completion: January 1, 2012
• Last Updated: August 16, 2011

Record last verified: 2010-06