Social Media Posts About Cancer: Five Timepoints

NCT07588607 | Completed DMC

• 1 other identifier: 25-0269-5TP
• Study Type: interventional
• Target: 294
• Locations: 1 country
• Sites: 1

Brief Summary

The main purpose of this trial was to evaluate the impact of user interface designs on intervening with cancer misinformation on social media. The investigators conducted a randomized clinical trial with a sample of 294 US adults (ages 18-65) who previously had a cancer diagnosis or were a cancer caregiver. This registration record only covers the 5 timepoint trial under the same IRB number.

Conditions

Cancer

Keywords

Communication; Social media; Cancer misinformation; Misinformation

Outcome Measures

Primary Outcomes (2)

• Flagging

  Measured with intervening behavior, defined as the flag icon selected. Response options were no (coded as 0) or yes (coded as 1). Assessed 15 times. Assessed for 2 cancer misinformation posts and 1 cancer support post at each timepoint approximately 2 business days apart, starting on the day of enrollment.

  Up to 2 weeks

• Willingness to flag

  Measured with 1 self-reported survey item: "How willing are you to flag this post?" Responses ranged from "not at all" (coded as 1) to "extremely" (5). Assessed 15 times. Assessed for 2 cancer misinformation posts and 1 cancer support post at each timepoint approximately 2 business days apart, starting on the day of enrollment.

  Up to 2 weeks

Secondary Outcomes (12)

• Disliking

  Up to 2 weeks

• Liking

  Up to 2 weeks

• Willingness to dislike

  Up to 2 weeks

• Willingness to like

  Up to 2 weeks

• Willingness to comment

  Up to 2 weeks

Study Arms (3)

Social cue prompts and policy

EXPERIMENTAL

Participants are exposed to the social cue prompts and policy intervention with cancer misinformation posts.

Behavioral: Social cue prompt and policy

Standard prompts

EXPERIMENTAL

Participants are exposed to the standard prompts intervention with cancer misinformation posts.

Behavioral: Standard prompts

Control

NO INTERVENTION

Participants do not see prompts on cancer misinformation posts.

Interventions

Social cue prompt and policy BEHAVIORAL

Cancer misinformation posts are shown with a prompt above the post caption that read, "This post has been flagged as false and potentially harmful by \[47 or 48\] people on Invibe. If you want to report, click the flag below." The social media launch screen had an overlaid policy for removing flagged posts: "We are committed to working with you and others on Invibe to reduce false and potentially harmful information. When a post is flagged by 50 people, we remove it until we verify the information. Please help us make the Invibe experience a good one for all."

Social cue prompts and policy

Standard prompts BEHAVIORAL

Cancer misinformation posts are shown with a prompt above the post caption that read, "This post has been flagged as false and potentially harmful. If you want to report, click the flag below."

Standard prompts

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Are ages 18-65
• Received a cancer diagnosis or have been a cancer caregiver
• Used social media
• Were willing to complete all five study timepoints
• Resided in the United States

You may not qualify if:

• \- Were unable to scroll to see posts on Invibe in the screener survey

Sponsors & Collaborators

• UNC Lineberger Comprehensive Cancer Center: lead

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States

Location

Related Links

• University of North Carolina Lineberger Comprehensive Cancer Center Clinical Trials
• AsPredicted.com on March 24, 2025

MeSH Terms

Conditions

Neoplasms; Communication

Interventions

Policy

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Health Care Economics and Organizations

Study Officials

• Allison J Lazard, PhD

  UNC Lineberger Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2026
• First Posted: May 15, 2026
• Study Start: March 31, 2025
• Primary Completion: May 12, 2025
• Study Completion: May 12, 2025
• Last Updated: May 15, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: CSR

Locations

US (1)