Evaluation of Treatment Outcomes of Interceptive Orthodontic Intervention for Class Iii Malocclusion Using Inclined Plane Appliance Combined With Variable Bracket Placement

NCT07581990 | Completed

• 1 other identifier: Prof. Le Nguyen Lam CTUMP
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

Study Title: Evaluation of Treatment Outcomes of Interceptive Orthodontic Intervention for Class III Malocclusion Using Inclined Plane Appliance Combined With Variable Bracket Placement Objective: To evaluate the clinical and radiographic outcomes of interceptive orthodontic treatment for skeletal Class III malocclusion in children Participants: Children aged 7 to 12 years diagnosed with skeletal Class III malocclusion (ANB \< 0°, Wits \< -2mm) and cervical vertebral maturation stages CS1, CS2, or CS3, treated at the Ho Chi Minh City Hospital of Odonto-Stomatology from 2025 to 2026 Methodology: This is a descriptive study with a non-controlled clinical intervention The treatment involves the application of a fixed inclined plane appliance on the mandibular teeth combined with variable bracket placement (bonded at a 180-degree rotation) on the maxillary anterior teeth to promote the forward movement of the upper incisors and stimulate maxillary alveolar bone growth Evaluation: Treatment efficacy is assessed after 6 months by comparing skeletal, dental, and soft tissue changes using standardized lateral cephalometric radiographs and Cone Beam Computed Tomography (CBCT) Success is defined by achieving a positive overjet (≥2mm), overbite (≥2mm), and an Angle Class I molar relationship

Conditions

Class III Malocclusion; Facemask; Inclined Plane Appliance

Outcome Measures

Primary Outcomes (1)

• Treatment success of interceptive orthodontic intervention for skeletal Class III malocclusion

  Evaluation of treatment success based on clinical and radiographic criteria. Success is defined as achieving: Positive overjet (OJ ≥ 2mm) . Positive overbite (OB ≥ 2mm) . Angle Class I molar relationship . The assessment includes measuring changes in skeletal, dental, and soft tissue parameters using standardized lateral cephalometric radiographs and Cone Beam Computed Tomography (CBCT)

  6 months after the start of the intervention

Study Arms (1)

Inclined Plane and Variable Bracket placement group

EXPERIMENTAL

Other: Inclined Plane Appliance Combined With Variable Bracket Placement

Interventions

Inclined Plane Appliance Combined With Variable Bracket Placement OTHER

The treatment involves a combination of a fixed inclined plane appliance on the mandibular anterior teeth and variable bracket placement (brackets bonded with a 180-degree rotation) on the maxillary incisors . This protocol aims to promote forward maxillary growth and improve the dental relationship

Inclined Plane and Variable Bracket placement group

Eligibility Criteria

• Age: 7 Years - 12 Years
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Age: Patients between 7 and 12 years old
• Skeletal Maturity: Cervical vertebral maturation (CVM) stages CS1, CS2, or CS3
• Diagnosis: Diagnosed with skeletal Class III malocclusion on lateral cephalometric radiographs, characterized by an ANB angle \< 0° and a Wits appraisal \< -2mm
• Patients and their legal guardians provide informed consent to participate in the study

You may not qualify if:

• Dental Characteristics: Absence of anterior crossbite
• Eruption Status: Permanent maxillary central incisors have not yet erupted
• Molar Relationship: Molar relationship is not Class III according to Edward H. Angle's classification
• Skeletal/Growth Issues: Excessive mandibular growth
• Congenital Conditions: Congenitally missing maxillary first molars or presence of cleft lip and/or palate

Sponsors & Collaborators

• Can Tho University of Medicine and Pharmacy: lead

Study Sites (1)

Department of Orthodontics, Ho Chi Minh City Dental Hospital

Ho Chi Minh City, Vietnam

Location

Related Links

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MeSH Terms

Conditions

Malocclusion, Angle Class III

Condition Hierarchy (Ancestors)

Malocclusion; Tooth Diseases; Stomatognathic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2026
• First Posted: May 12, 2026
• Study Start: July 20, 2025
• Primary Completion: April 20, 2026
• Study Completion: April 20, 2026
• Last Updated: May 13, 2026

Record last verified: 2026-05

Locations

VN (1)