Combined Effects of Tactile Kinesthetic Stimulation With Neural Mobilization in Stroke Patients

NCT07578961 | Active Not Recruiting

• 1 other identifier: REC/RCR&AHS/25/0216
• Study Type: interventional
• Target: 53
• Locations: 1 country
• Sites: 1

Brief Summary

Combined Effects of Tactile -kinesthetic stimulation with Neural mobilization on sensory and motor functions of upper limb in stroke patients

Conditions

Stroke

Keywords

Chronic stroke rehabilitation; neural mobilization; tactile kinesthetic stimulation; tactile therapy

Outcome Measures

Primary Outcomes (2)

• 1.Fugl-Meyer Assessment (FMA)

  The Fugl-Meyer Assessment (FMA) was developed specifically for stroke survivors and is a performance-based tool that gauges sensorimotor deficits in people living with hemiplegia. The FMA examines five key areas: voluntary motor control, sensory perception, balance, passive joint range of motion, and joint-related pain. Within this battery, the motor section commands the most attention; it rates movement, coordination, and reflex activity in the arms and legs, yielding a ceiling score of 100 points (66 for the arm and 34 for the leg).

  baseline with 4 week

• 2.Nottingham Sensory Assessment (NSA)

  The Nottingham Sensory Assessment, or NSA, provides clinicians with a standard method for mapping sensory loss after a stroke. Designed to examine both arms and legs, it centers on three core domains: touch, proprioception, and stereognosis. Within the protocol, practitioners test responses to light touch, gentle pressure, pinprick, temperature changes, and passive joint positioning. Because around half of all stroke survivors carry hidden somatosensory deficits that often impede movement, the tool is essential for early identification.

  baseline with 4 week

Study Arms (2)

Combine effects of Tactile with neural of sensory and motor functions of upper limb stroke

EXPERIMENTAL

Tactile Kinesthetic with Neural Mobilization: participants receive TKS WITH NM for 20 mins for 3 days per week for 4 weeks

Other: Tactile kinesthetic stimulation with neural mobilization

Combine effects of Tactile with neural mobilization of sensory and motor functions of upper limb str

ACTIVE COMPARATOR

Tks With Nm receive 20 mins therapy for 3 days per week

Other: kinesthetic therapy

Interventions

Tactile kinesthetic stimulation with neural mobilization OTHER

The therapist rests a light touch on the limb, applying only the weight of fingertips Soft, gliding strokes travel across the skin, delivered with the very tips of the fingers Pressure remains steadily upon targeted patches of tissue without sliding away Measured, rhythmical strokes creep up and down the length of the arm or leg Smooth silk, rough jute, coarse sponge, and other materials are brushed over the skin in turn.Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder.

Combine effects of Tactile with neural of sensory and motor functions of upper limb stroke

kinesthetic therapy OTHER

Median nerve mobilization: Slowly glide the median nerve by extending wrist and fingers while gently abducting the shoulder. Ulnar nerve mobilization: Control elbow flexion and wrist extension while holding shoulder in slight abduction Radial nerve mobilization: Passively flex the wrist, pronate the forearm, and depress the shoulder to slide the radial nerve

Combine effects of Tactile with neural mobilization of sensory and motor functions of upper limb str

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age between 45 - 65 years
• Both gender Male and Female
• Diagnosed with chronic stroke stated as occurring 6 month to 12 month .
• Sensory impairment - loss of tactile and proprioception NSA ( \< 7/12)
• Motor impairment - lack in full strength and coordination ( Brunnstrom \>3)
• Scored 24 or higher on the Mini-Mental State Examination, indicating sufficient cognition to follow study instructions.

You may not qualify if:

• Severe cognitive or communication difficulties that would prevent meaningful involvement in therapy or testing.
• Comorbid conditions that impair upper-limb function, including arthritis, prior fractures, or similar disorders.
• Neurological conditions other than stroke that could interfere with study outcomes
• Engagement in any other rehabilitation program during the trial period.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Unknown Facility

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (3)

• Battesha HHM, Wadee AN, Shafeek MM, Tawfick AM, Ibrahim HM. Maze Control Training on Kinesthetic Awareness in Patients with Stroke: A Randomized Controlled Trial. Rehabil Res Pract. 2022 Feb 24;2022:5063492. doi: 10.1155/2022/5063492. eCollection 2022.

  PMID: 35251715 BACKGROUND

• Takahashi R, Koiwa M, Ide W, Okawada M, Akaboshi K, Kaneko F. Visually Induced Kinaesthetic Illusion Combined with Therapeutic Exercise for Patients with Chronic Stroke: A Pilot Study. J Rehabil Med. 2022 Apr 7;54:jrm00276. doi: 10.2340/jrm.v54.29.

  PMID: 35266005 BACKGROUND

• Afzal MR, Pyo S, Oh MK, Park YS, Yoon J. Evaluating the effects of delivering integrated kinesthetic and tactile cues to individuals with unilateral hemiparetic stroke during overground walking. J Neuroeng Rehabil. 2018 Apr 16;15(1):33. doi: 10.1186/s12984-018-0372-0.

  PMID: 29661237 BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Sabiha Arshad, Ms

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: May 11, 2026
• Study Start: April 5, 2025
• Primary Completion (Estimated): June 3, 2026
• Study Completion (Estimated): July 6, 2026
• Last Updated: May 11, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)