A Study Of Starting Strength Barbell Training

NCT07578285 | Recruiting

• 1 other identifier: 26-001184
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure.

Conditions

Blood Pressure; Lipid Profile; Fasting Glucose

Outcome Measures

Primary Outcomes (2)

• Change in systolic blood pressure

  Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)

  Baseline, 16 weeks

• Change in diastolic blood pressure

  Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)

  Baseline, 16 weeks

Secondary Outcomes (5)

• Change in total cholesterol

  Baseline, 16 weeks

• Change in low-density lipoprotein cholesterol (LDL-C)

  Baseline, 16 weeks

• Change in high-density lipoprotein cholesterol (HDL-C)

  Baseline, 16 weeks

• Change in triglycerides

  Baseline, 16 weeks

• Change in fasting glucose

  Baseline, 16 weeks

Study Arms (1)

Starting Strength barbell training program

EXPERIMENTAL

12-week coached, progressive overload barbell strength training program (Starting Strength)

Other: Progressive Barbell Strength Training

Interventions

Progressive Barbell Strength Training OTHER

Subjects will participate in a 12-week barbell training program, 3 days per week for approximately 60 minutes each session. Training sessions will be conducted by Starting Strength certified coaches at Starting Strength Scottsdale gym. Core barbell movements including but not limited to: squat, deadlift, bench press, overhead press, and power clean.

Starting Strength barbell training program

Eligibility Criteria

• Age: 15 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-100 years
• Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week)
• No participation in structured resistance training programs within the past 6 months.
• Able to safely participate in resistance training as determined by medical screening
• Willing to commit to 3 training sessions per week for 12 weeks
• Able to provide informed consent
• Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company.

You may not qualify if:

• Current participation in structured resistance training programs
• Cardiovascular disease requiring activity restriction
• Uncontrolled hypertension (systolic BP \>180 mm Hg or diastolic BP \>110 mm Hg)
• Musculoskeletal conditions precluding safe barbell training
• Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment
• Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training

Sponsors & Collaborators

• Mayo Clinic: lead

Study Sites (1)

Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States

RECRUITING

Related Links

• Mayo Clinic Clinical Trials

Study Officials

• Joshua Lee, PA-C,MPAS

  Mayo Clinic

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Joshua Lee, PA-C,MPAS

CONTACT

480-342-0612; Lee.Joshua2@mayo.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: May 11, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): January 1, 2028
• Study Completion (Estimated): January 1, 2029
• Last Updated: May 11, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)