NCT07489417

Brief Summary

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
14mo left

Started Mar 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress16%
Mar 2026Aug 2027

Study Start

First participant enrolled

March 4, 2026

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

March 15, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 24, 2026

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

March 24, 2026

Status Verified

March 1, 2026

Enrollment Period

1.4 years

First QC Date

March 15, 2026

Last Update Submit

March 17, 2026

Conditions

SleepBlood Pressure

Keywords

SleepBlood pressure

Outcome Measures

Primary Outcomes (1)

  • Blood Pressure

    Blood pressure

    Baseline and during the last 1-minute of stress

Study Arms (2)

Sleep Restriction

EXPERIMENTAL

You will be asked to shorten your sleep to four hours.

Behavioral: Sleep Restriction

Normal Sleep

NO INTERVENTION

You will be asked to sleep for 7-9 hours.

Interventions

Sleep RestrictionBEHAVIORAL

You will be asked to shorten your sleep to four hours.

Sleep Restriction

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy adult men and women
  • years of age
  • BMI \< 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
  • Non-pregnant, non-breastfeeding, and non-nicotine users
  • Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
  • Premenopausal

You may not qualify if:

  • No acute or chronic conditions
  • Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
  • Self-reported history of irregular sleep
  • Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Missouri

Columbia, Missouri, 65211, United States

RECRUITING

Central Study Contacts

Jacqueline Limberg

CONTACT

1-573-882-2544limberglab@missouri.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 15, 2026

First Posted

March 24, 2026

Study Start

March 4, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

March 24, 2026

Record last verified: 2026-03

Locations

US(1)