Baseline Anxiety Trajectories in Pediatric Radiation Therapy Observational Cohort

NCT07575815 | Not Yet Recruiting

• 2 other identifiers: 2026-0247NCI-2026-03503
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

This is a prospective, observational cohort study of pediatric patients ages 2-12 undergoing radiation therapy at MD Anderson Cancer Center.

Conditions

Anxiety; Radiation

Outcome Measures

Primary Outcomes (1)

• Safety and Adverse Events (AEs)

  Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0

  Through study completion; an average of 1 year.

Eligibility Criteria

• Age: 2 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

UT MD Anderson patients

You may qualify if:

• To be eligible to participate in this study, an individual must meet all of the following criteria:
• Provision of signed and dated informed consent from a parent or legal guardian.
• For children age 7 and older, provision of informed assent in addition to parental consent, consistent with institutional guidelines.
• Stated willingness of parent/guardian and child (as appropriate) to comply with study procedures (i.e., observation during scheduled radiation therapy appointments).
• Male or female, ages 2-12 years.
• Scheduled to undergo radiation therapy at MD Anderson Cancer Center.

You may not qualify if:

• An individual who meets any of the following criteria will be excluded from participation in this study:
• Has already completed the simulation session for radiation therapy prior to enrollment.
• Declines parental consent or, when applicable, child assent.

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

UT MD Anderson

Houston, Texas, 77030, United States

Location

Related Links

• UT MD Anderson Website

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

• Susan L McGovern, MD, PHD

  UT MD Anderson

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Susan L McGovern, MD, PHD

CONTACT

(713) 563-2336; slmcgove@mdanderson.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2026
• First Posted: May 8, 2026
• Study Start (Estimated): October 1, 2026
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 1, 2029
• Last Updated: May 8, 2026

Record last verified: 2026-05

Locations

US (1)