NCT06295783

Brief Summary

To learn more about how you would rate the intensity or severity of your symptoms during or after radiation therapy using questionnaires with different rating scales.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
9mo left

Started Jun 2024

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress72%
Jun 2024Feb 2027

First Submitted

Initial submission to the registry

February 29, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 6, 2024

Completed
3 months until next milestone

Study Start

First participant enrolled

June 10, 2024

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2026

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2027

Expected
Last Updated

January 14, 2026

Status Verified

January 1, 2026

Enrollment Period

1.6 years

First QC Date

February 29, 2024

Last Update Submit

January 13, 2026

Conditions

Radiation

Outcome Measures

Primary Outcomes (1)

  • Safety and adverse events (AEs)

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE)

    Through study completion; an average of 1 year

Study Arms (1)

Head and Neck Cancer (HNC) Questionnaire

Participants will be asked to fill out three head and neck cancer (HNC) questionnaires during your visits to the clinic: 1. The MDASI-HN questionnaire (standard-of-care) has 28 questions. 2. The EORTC QLQ-HN35 questionnaire has 35 questions. 3. The EORTC QLQ-30 questionnaire has 30 questions.

Other: MDASI-HNOther: EORTC QLQ-C30Other: EORTC HN35

Interventions

MDASI-HNOTHER

Given by Questionnaire

Head and Neck Cancer (HNC) Questionnaire
EORTC QLQ-C30OTHER

Given by Questionnaire

Head and Neck Cancer (HNC) Questionnaire
EORTC HN35OTHER

Given by Questionnaire

Head and Neck Cancer (HNC) Questionnaire

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Head and Neck Cancer (HNC) participants undergoing active radiation therapy.

You may qualify if:

  • Age ≥18 years
  • English as a primary language
  • Participants with a diagnosis of HNC undergoing active curative RT or having received curative RT within the past 5 years at MD Anderson
  • Ability to complete the survey(s) of their own volition

You may not qualify if:

  • Age \< 18 years
  • Non-English speaking participants
  • Participants who are receiving or have received RT in a non-HN site.
  • Participants in follow up and over 5 years from post-treatment
  • Neurocognitive deficits that render patients unable to complete the survey(s) on their own.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

Study Officials

  • Amy Moreno, MD

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Amy Moreno, MD

CONTACT

(713) 745-4590akmoreno@mdanderson.org

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 29, 2024

First Posted

March 6, 2024

Study Start

June 10, 2024

Primary Completion

February 1, 2026

Study Completion (Estimated)

February 1, 2027

Last Updated

January 14, 2026

Record last verified: 2026-01

Locations

US(1)