NCT07572942

Brief Summary

This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS). The developed assessment protocol integrates visuospatial processing, reaction time, and upper extremity motor control within a single task. Construct validity will be examined through correlations with reaction time and proprioception measurements, and test-retest reliability will be assessed to determine measurement consistency.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for all trials

Timeline
2mo left

Started Apr 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress26%
Apr 2026Jul 2026

Study Start

First participant enrolled

April 15, 2026

Completed
13 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 28, 2026

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

May 1, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 7, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2026

Expected
Last Updated

May 7, 2026

Status Verified

May 1, 2026

Enrollment Period

13 days

First QC Date

May 1, 2026

Last Update Submit

May 1, 2026

Conditions

Motoric Cognitive Risk SyndromeCognitive-Motor InteractionSensorimotor Performance

Outcome Measures

Primary Outcomes (1)

  • Visual-laser feedback map test performance

    Performance parameters including completion time (seconds), reaction time (milliseconds), movement accuracy, and total performance score obtained from the figure-of-eight tracing and directional target tracking tasks.

    Baseline

Secondary Outcomes (4)

  • Reaction time

    Baseline

  • Shoulder proprioception

    Baseline

  • Test-retest reliability

    Baseline and 7-day follow-up

  • Measurement error

    Baseline and 7-day follow-up

Study Arms (1)

Motoric Cognitive Risk Syndrome Group

Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome (MCRS) will be included. Participants will undergo neuroscience-based visual-laser feedback map tests along with reaction time and proprioception assessments under standardized conditions. No therapeutic intervention will be applied.

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be recruited from the Tazelenme University Coordination Unit in Balıkesir, Turkey. The study population represents individuals at risk of cognitive decline but without diagnosed dementia, enabling the evaluation of early-stage cognitive-motor interaction.

You may qualify if:

  • Aged ≥65 years Diagnosis of Motoric Cognitive Risk Syndrome (subjective cognitive complaint + slow gait) Living independently in the community Able to understand and perform test procedures

You may not qualify if:

  • Diagnosed dementia Severe psychiatric disorders Advanced visual impairments (e.g., macular degeneration, severe cataract) Neurological disorders affecting motor control Severe tremor or ataxia interfering with task performance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Balikesir University

Balıkesir, Bigadiç, Turkey (Türkiye)

RECRUITING

Related Publications (6)

  • Pinzón-Ríos, I. D., & Moreno-Collazos, J. E. (2020). Neural aging, brain plasticity and exercise: Advances from a physiotherapy perspective. Archivos de Medicina (Manizales), 20(1), 188-202.

    BACKGROUND

  • Koo, T. K., & Li, M. Y. (2016). A guideline of selecting and reporting intraclass correlation coefficients for reliability research. Journal of Chiropractic Medicine, 15(2), 155-163. https://doi.org/10.1016/j.jcm.2016.02.012

    BACKGROUND

  • Shadmehr, R., & Krakauer, J. W. (2008). A computational neuroanatomy for motor control. Experimental Brain Research, 185(3), 359-381. https://doi.org/10.1007/s00221-008-1280-5

    BACKGROUND

  • Moinuddin, A., Goel, A., & Sethi, Y. (2021). The role of augmented feedback on motor learning: A systematic review. Cureus, 13(11), e19695. https://doi.org/10.7759/cureus.19695

    BACKGROUND

  • Clark, D. J. (2015). Automaticity of walking: Functional significance, mechanisms, measurement and rehabilitation strategies. Frontiers in Human Neuroscience, 9, 246. https://doi.org/10.3389/fnhum.2015.00246

    BACKGROUND

  • Seidler, R. D., Bernard, J. A., Burutolu, T. B., et al. (2010). Motor control and aging: Links to age-related brain structural, functional, and biochemical effects. Neuroscience & Biobehavioral Reviews, 34(5), 721-733. https://doi.org/10.1016/j.neubiorev.2009.10.005

    BACKGROUND

Central Study Contacts

Ebru Tekin, Lecturer

CONTACT

+90 266 614 69 11ebrutekin123@gmail.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

May 1, 2026

First Posted

May 7, 2026

Study Start

April 15, 2026

Primary Completion

April 28, 2026

Study Completion (Estimated)

July 15, 2026

Last Updated

May 7, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)