NCT07572968

Brief Summary

This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. The study evaluates cognitive-motor interference and dual-task cost to better understand early markers of cognitive decline and fall risk.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for all trials

Timeline
2mo left

Started Apr 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress26%
Apr 2026Jul 2026

Study Start

First participant enrolled

April 15, 2026

Completed
13 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 28, 2026

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

May 1, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 7, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2026

Expected
Last Updated

May 7, 2026

Status Verified

May 1, 2026

Enrollment Period

13 days

First QC Date

May 1, 2026

Last Update Submit

May 1, 2026

Conditions

Motoric Cognitive Risk SyndromeDual-Task PerformanceGaitBalance

Outcome Measures

Primary Outcomes (1)

  • Timed Up and Go (TUG) performance

    Functional mobility will be assessed using the Timed Up and Go (TUG) test. Participants will stand up from a standard chair (approximately 46 cm), walk 3 meters, turn around a marker, return, and sit down. Performance time will be recorded in seconds under three conditions: single-task (baseline), physical dual-task (carrying a cup of water), and cognitive dual-task (serial subtraction task).

    Baseline (single session assessment)

Secondary Outcomes (4)

  • Tandem walking test performance

    Baseline

  • Dual-task cost (%)

    Baseline

  • Gait speed

    Baseline

  • Cognitive-motor interference

    Baseline

Study Arms (1)

Motoric Cognitive Risk Syndrome Group

Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be included. Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. No intervention will be applied.

Other: Assessment Protocol

Interventions

Assessment ProtocolOTHER

Participants will undergo standardized Timed Up and Go (TUG) and tandem walking assessments under single-task and dual-task conditions. Cognitive dual-task conditions will include serial subtraction while performing the motor task. No therapeutic intervention, exercise training, or treatment will be applied.

Motoric Cognitive Risk Syndrome Group

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome in Balıkesir, Turkey.

You may qualify if:

  • Age ≥ 65 years Subjective cognitive complaints Slow gait speed No dementia diagnosis

You may not qualify if:

  • Severe visual/hearing impairment Neurological diseases (stroke, Parkinson) Acute orthopedic conditions affecting walking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Balikesir University

Balıkesir, Bigadiç, Turkey (Türkiye)

RECRUITING

Related Publications (5)

  • Sekhon, H., Allali, G., & Beauchet, O. (2022). Dual-task cost of gait in Motoric Cognitive Risk Syndrome: A cross-sectional study. Frontiers in Aging Neuroscience, 14, 843575.

    BACKGROUND

  • Montero-Odasso, M., Almeida, Q. J., Burhan, A. M., Camicioli, R., Doyon, J., Fraser, S., et al. (2020). Gait and cognition: The dual-task approach as a window into the aging brain. The Journals of Gerontology Series A, 75(11), 2157-2165.

    BACKGROUND

  • Beauchet, O., Sekhon, H., Launay, C. P., Chabot, J., & Allali, G. (2022). Gait variability and Motoric Cognitive Risk Syndrome: A systematic review. Frontiers in Aging Neuroscience, 14, 856004.

    BACKGROUND

  • Beauchet, O., Allali, G., Sekhon, H., Verghese, J., Guilain, S., Steinmetz, J. P., & Launay, C. P. (2021). Motoric Cognitive Risk Syndrome and incident dementia: Results from a comparative meta-analysis. Journal of the American Medical Directors Association, 22(8), 1642-1649.

    BACKGROUND

  • Allali, G., Aybek, S., Launay, C. P., Adam, S., Azizy, M., & Beauchet, O. (2023). Cognitive-gait interference in pre-dementia syndromes: A systematic review. Journal of Alzheimer's Disease, 92(1), 15-28.

    BACKGROUND

MeSH Terms

Interventions

Nursing Assessment

Intervention Hierarchy (Ancestors)

Nursing ProcessComprehensive Health CarePatient Care ManagementHealth Services Administration

Central Study Contacts

Ebru Tekin, Lecturer

CONTACT

+90 266 614 69 11ebrutekin123@gmail.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

May 1, 2026

First Posted

May 7, 2026

Study Start

April 15, 2026

Primary Completion

April 28, 2026

Study Completion (Estimated)

July 15, 2026

Last Updated

May 7, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)