Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease

NCT07568951 | Recruiting

• 1 other identifier: 202202289A3
• Study Type: observational
• Target: 210
• Locations: 1 country
• Sites: 2

Brief Summary

Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations. While previous studies have mainly focused on sagittal plane balance, the contribution of hip abductor muscles remains unclear, especially regarding their force production and control abilities. Therefore, this study aims to investigate hip abductor muscle force production and force control, and to examine whether these factors are associated with postural control, gait, and balance performance in individuals across different ages and those with PD.

Conditions

Aging; Parkinson's Disease (PD)

Keywords

Old; Parkinson's disease; muscle force; force steadiness; balance; gait performance

Outcome Measures

Primary Outcomes (13)

• Maximal force

  The maximal force of lower extremity muscles

  Baseline

• Rate of torque development

  The ability to rapidly generate muscle force

  Baseline

• Force steadiness

  The ability to maintain a constant force output during a submaximal contraction

  Baseline

• Walking speed

  The time taken by participants to walk a standardized distance

  Baseline

• Step Length

  The linear distance between the two ankles, typically expressed in centimeter(cm).

  Baseline

• Cadence

  The number of steps taken per minute (SPM)

  Baseline

• Single Support Time

  The duration within the gait cycle when only one foot is in contact with the ground, typically measured in seconds or as a percentage of the total gait cycle.

  Baseline

• Double Support Time

  The portion of the gait cycle where both feet are in contact with the ground, indicating the transition phase between steps, expressed as a percentage of the gait cycle or in seconds.

  Baseline

• Swing Time

  The portion of the gait cycle where the foot is not in contact with the ground, moving forward to the next step. It is usually expressed as a percentage of the total gait cycle or in seconds.

  Baseline

• COP Velocity in Balance Tasks

  The speed at which the COP moves, calculated over the duration of the balance task. Higher velocities may reflect more dynamic balance adjustments or instability. Unit：millimeter per second(mm/s)

  Baseline

• COP Area in Balance Tasks

  The area covered by the COP trajectory during the balance task, providing an estimate of the sway envelope. A larger area might indicate poorer balance control. Unit：square millimeter(mm\^2)

  Baseline

• Timed Up-and-Go Test

  Tthe time an individual takes to stand up from a chair, walk 3 meters, turn around, walk back, and sit down.

  Baseline

• Four Square Step Test

  Participants will be required to perform four square step test by changing directions while stepping forward, sideway, and backward over a low obstacle as fast as possible.

  Baseline

Study Arms (1)

Healthy people

General healthy adults

Other: Age; Other: Parkinson's disease (PD)

Interventions

Age OTHER

We compare the young, middle-aged, and old groups

Healthy people

Parkinson's disease (PD) OTHER

We compare the healthy group and PD group.

Healthy people

Eligibility Criteria

• Age: 20 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

This study recruits healthy elderly individuals, healthy middle-aged individuals, healthy young individuals, and individuals with PD.

You may qualify if:

• to 39 years (young), 40 to 59 years (young), and 60-85 years (old)
• generally in good health
• able to walk 10 m independently
• able to follow all instructions

You may not qualify if:

• neurologic, psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
• any pain over the lower extremities
• uncontrolled cardiovascular diseases
• unable to provide informed consent.
• clinical diagnosis of idiopathic PD
• Hoehn and Yahr stages 1 to 3
• stable anti-PD medications
• able to walk 10 m independently
• able to follow all instructions
• psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
• neurological conditions other than PD
• any pain over the lower extremities
• uncontrolled cardiovascular diseases
• unable to provide informed consent.

Sponsors & Collaborators

• Chang Gung Memorial Hospital: lead
• Chang Gung University: collaborator

Study Sites (2)

Chang Gung Memorial Hospital

Taoyuan, Taiwan

RECRUITING

Chang Gung University

Taoyuan, Taiwan

RECRUITING

MeSH Terms

Conditions

Parkinson Disease

Interventions

Aging; Mental Status and Dementia Tests

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Intervention Hierarchy (Ancestors)

Growth and Development; Physiological Phenomena; Neuropsychological Tests; Psychological Tests; Behavioral Disciplines and Activities

Study Officials

• Chu-Ling Yen

  Chang Gung University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Chu-Ling Yen

CONTACT

886-3-2118800; clyen@mail.cgu.edu.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: April 25, 2026
• First Posted: May 6, 2026
• Study Start: August 1, 2023
• Primary Completion (Estimated): July 31, 2029
• Study Completion (Estimated): July 31, 2029
• Last Updated: May 6, 2026

Record last verified: 2026-05

Locations

TW (2)