Clinical Scores, Biomarkers, and CT Findings in Acute Pulmonary Embolism

NCT07566858 | Not Yet Recruiting

• 1 other identifier: PE-Score-CT-2025
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to compare clinical scoring systems, laboratory biomarkers, and computed tomography (CT) findings in patients diagnosed with acute pulmonary embolism in different hospital departments. The study will include patients diagnosed with acute pulmonary embolism at Sohag University Hospital. Clinical data, laboratory results, and imaging findings will be collected and analyzed to evaluate their diagnostic and prognostic value. The goal of this research is to identify the most reliable and practical tools for early diagnosis and risk stratification of acute pulmonary embolism, which may help improve patient management and outcomes. This is an observational study and does not involve any intervention or change in standard patient care.

Conditions

Acute Pulmonary Embolism

Keywords

Acute Pulmonary Embolism; Pulmonary Embolism; CT Pulmonary Angiography; Clinical Scores; D-dimer

Outcome Measures

Primary Outcomes (1)

• Number of Participants with In-Hospital All-Cause Mortality

  All-cause mortality among adult patients with confirmed acute pulmonary embolism, defined as death from any cause occurring during hospitalization. The outcome will be assessed as the number of participants who die before hospital discharge.

  Up to 30 days

Study Arms (1)

Acute Pulmonary Embolism Group

This cohort includes patients diagnosed with acute pulmonary embolism at Sohag University Hospital. Participants will be evaluated using clinical scoring systems, laboratory biomarkers, and computed tomography pulmonary angiography (CTPA) findings. No interventions will be applied, and all data will be collected as part of routine clinical care for observational analysis.

Other: No Intervention (Observational Study Data Collection)

Interventions

No Intervention (Observational Study Data Collection) OTHER

This is an observational study with no active intervention. All data are collected from routine clinical care, including clinical scoring systems, laboratory biomarkers, and computed tomography pulmonary angiography (CTPA) findings in patients with acute pulmonary embolism.

Acute Pulmonary Embolism Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with confirmed acute pulmonary embolism admitted to Sohag University Hospital from different departments including Emergency, ICU, Medical, and Surgical wards.

You may qualify if:

• Adults aged ≥ 18 years
• Confirmed acute pulmonary embolism by CTPA

You may not qualify if:

• Chronic pulmonary embolism
• Non-diagnostic CTPA
• Refusal to participate
• Severe renal impairment precluding contrast-enhanced CT
• Known hypersensitivity to contrast media

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Pulmonary Embolism

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Chest Diseases

Study Record Dates

• First Submitted: April 4, 2026
• First Posted: May 5, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): May 1, 2027
• Study Completion (Estimated): July 1, 2027
• Last Updated: May 5, 2026

Record last verified: 2026-04