Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations

NCT07566676 | Recruiting

• 1 other identifier: 1333/833
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.

Conditions

Deep Bite Malocclusion; Intrusion of Tooth; Orthodontic Tooth Movement; Root Resorption

Outcome Measures

Primary Outcomes (2)

• Amount of root resorption

  Up to 6 months or correction of deep bite

• Marginal bone level changes

  Up to 6 months or correction of deep bite

Secondary Outcomes (1)

• Amount of intrusion of maxillary incisors

  Up to 6 months or correction of deep bite

Study Arms (2)

Maxillary incisor intrusion with utility arch assisted with micro-osteoperforations.

EXPERIMENTAL

Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets with application of micro-osteoperforations above the apices of maxillary incisors.

Procedure: Micro-osteoperforations

Maxillary incisor intrusion with utility arch without micro-osteoperforations

ACTIVE COMPARATOR

Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets without application of micro-osteoperforations.

Device: Utility arch

Interventions

Micro-osteoperforations PROCEDURE

Using utility arch with micro-osteoperforations (MOPs). The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increase bone resorption and the catabolic phase of tooth movement in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement at the apices above maxillary incisors to evaluate the amount of movement and amount of root resorption.

Also known as: MOPs

Maxillary incisor intrusion with utility arch assisted with micro-osteoperforations.

Utility arch DEVICE

Patients will receive utility arch for intrusion of maxillary incisors without micro-osteoperforations.

Maxillary incisor intrusion with utility arch without micro-osteoperforations

Eligibility Criteria

• Age: 15 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients age between 15-25 years.
• Patients with overbite ≥ 4 mm.
• All permanent teeth erupted (excluding 3rd molars).
• No previous orthodontic treatment.
• Patients with good oral hygiene and good periodontal health.

You may not qualify if:

• Skeletal discrepancies.
• Missing maxillary anterior teeth or any kind of tooth/root shape anomaly.
• Patients with root resorption or impacted canines.
• Previous history of orthodontic treatment.
• Systemic disease interferes with orthodontic tooth movement.
• History of trauma affecting the maxillary incisors.
• Poor oral hygiene or periodontally compromised patient.
• Endodontically treated upper anterior teeth.

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Faculty of Dental Medicine (Boys), Al-Azhar University

Cairo, Nasr City, 4434103, Egypt

RECRUITING

MeSH Terms

Conditions

Root Resorption

Interventions

morpholinopropane sulfonic acid

Condition Hierarchy (Ancestors)

Tooth Resorption; Tooth Diseases; Stomatognathic Diseases

Study Officials

• Hussein N.I Al khalifa, Professor, Vice Dean (Phd)

  Faculty of Dental medicine (Boys), Al-Azhar University, Cairo, Egypt

  STUDY DIRECTOR

• Raafat E. Mohamed, Prof, Head of Department (Phd)

  Faculty of Dental medicine (Boys), Al-Azhar University, Cairo, Egypt

  STUDY DIRECTOR

Central Study Contacts

Taha S.S Hossameldin, MSc Candidate

CONTACT

+201096667923; tahahossameldin.3.209@azhar.edu.eg

Hussein N.I Al khalifa, Professor, Vice Dean (Phd)

CONTACT

+201090302704; HusseinAlkhalifa.209@azhar.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, MSc Candidate in Orthodontics

Study Record Dates

• First Submitted: April 24, 2026
• First Posted: May 5, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): June 1, 2028
• Study Completion (Estimated): June 1, 2029
• Last Updated: May 5, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)