Intraoral Scan and CBCT-Aided Diagnosis of Dental Plaque and Caries

NCT07555223 | Recruiting

• 1 other identifier: ONZ-2024-0383
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective clinical study aims to evaluate the diagnostic accuracy of intraoral scans (IOS) for the detection of dental plaque and caries. The diagnostic performance of IOS will be compared with current clinical reference standards. For plaque assessment, IOS-based evaluation will be compared with plaque detection using disclosing agents. For caries detection, IOS (including white-light imaging and caries detection features) will be compared with conventional visual inspection and bitewing radiography. Adult patients aged 18 to 70 years will be included.

Conditions

Dental Plaque; Dental Caries

Outcome Measures

Primary Outcomes (1)

• Diagnostic Accuracy of Intraoral Scan for Dental Plaque Detection

  Diagnostic accuracy of intraoral scan compared with plaque assessment using disclosing agents.

  At baseline and 2 weeks

Secondary Outcomes (1)

• Agreement Between Intraoral Scan and Reference Standard for Dental Caries Detection

  At baseline and 2 weeks

Study Arms (1)

Study Participants

All participants undergo intraoral scanning, visual inspection, plaque disclosure, and bitewing radiography for the assessment of dental plaque and caries.

Diagnostic Test: intraoral scan

Interventions

intraoral scan DIAGNOSTIC_TEST

intraoral scanning used for assessment of dental plaque and caries.

Study Participants

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients aged 18 to 70 years undergoing intraoral examination in a clinical setting, with at least 20 teeth, who are not pregnant and able to provide informed consent.

You may qualify if:

• Adults aged 18 to 70 years
• Not pregnant and not planning pregnant
• At least 20 teeth present
• Ability to provide informed consent

You may not qualify if:

• Conditions that prevent proper intraoral examination (e.g., severe gag reflex, limited mouth opening)
• patient unable to provide informed consent

Sponsors & Collaborators

• University Ghent: lead

Study Sites (1)

Tandarts Praktijk VERVACK

Wondelgem, Botestraat, 104, Belgium

RECRUITING

MeSH Terms

Conditions

Dental Plaque; Dental Caries

Condition Hierarchy (Ancestors)

Dental Deposits; Tooth Diseases; Stomatognathic Diseases; Tooth Demineralization

Central Study Contacts

sachiko maemoto

CONTACT

+32 93 32 40 57; Sachiko.Maemoto@ugent.be

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 21, 2026
• First Posted: April 29, 2026
• Study Start: April 3, 2025
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): July 1, 2027
• Last Updated: April 29, 2026

Record last verified: 2026-04

Locations

BE (1)