AN EXTENDED COHORT STUDY TO INVESTIGATE SUICIDAL BEHAVIOR IN SPAIN (THE SURVIVE 2 STUDY)

NCT07554729 | Recruiting

• 2 other identifiers: 2023/11342/IPI23/00147
• Study Type: observational
• Target: 3,600
• Locations: 1 country
• Sites: 2

Brief Summary

The goal of this observational study is to learn more about people who come to emergency departments in Spain after a suicide attempt and to find ways to prevent another attempt. The main questions are whether some personal, social, biological, and clinical factors are linked to a higher risk of trying again, and whether different follow-up strategies can help lower this risk over time. Researchers will follow a total of about 3,600 people who attempted suicide: around 1,800 who were already recruited in a previous study and about 1,800 new participants who will be added in this project, in several hospitals across Spain. Some participants may also be invited to give blood samples, answer online questionnaires, or use smartphone-based tools to understand better changes in mood and suicidal thoughts in daily life. A subset of participants may be invited to join separate clinical trials that test different follow-up programs to prevent another suicide attempt; these trials will be registered and described in their own study records.

Conditions

Suicidal Behaviors

Keywords

suicide; cohort study

Outcome Measures

Primary Outcomes (1)

• Columbia Suicide Severity Rating Scale (C-SSRS)

  The Columbia-Suicide Severity Rating Scale (C-SSRS) is a brief, structured interview that uses simple questions about suicidal thoughts and behaviors to identify whether someone is at risk for suicide and how severe and urgent that risk is.

  1 year

Secondary Outcomes (18)

• Patient Health Questionnaire (PHQ-9)

  1 year

• Generalized Anxiety Disorder (GAD-7)

  1 year

• McLean Screening Instrument for BPD (MSI-BPD)

  1 year

• Bruha Life Events

  1 year

• Childhood Trauma Questionnaire (CTQ-SF)

  baseline

Study Arms (1)

Suicide attempt cohort

Adults and adolescents who present to participating Spanish hospitals after a suicide attempt and are enrolled in the SURVIVE cohort. This group includes about 1,800 participants from a previous study and about 1,800 newly recruited participants, all followed for up to 3 years.

Eligibility Criteria

• Age: 12 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals (adolescents and adults) who present to the emergency departments of participating hospitals in Spain after a suicide attempt. The study will follow approximately 3,600 participants (about 1,800 already enrolled in a previous cohort and about 1,800 newly recruited) for up to 3 years to examine suicidal behavior and related risk and protective factors

You may qualify if:

• Individuals (above 12 years old) who present to participating Spanish hospital emergency departments after a suicide attempt, as defined by self-injurious behavior with at least some intent to die.
• Able to understand the study procedures and provide informed consent (or assent with parental/guardian consent for minors, according to local regulations)
• Sufficient proficiency in Spanish to complete study assessments

You may not qualify if:

• Suicide attempts clearly judged as accidental or without suicidal intent
• Severe cognitive impairment, intellectual disability, or neurological condition that, in the opinion of the clinical team, prevents valid assessment or informed consent
• Acute medical instability that makes participation in research procedures unsafe.
• Any condition or circumstance that, in the opinion of investigators, would seriously interfere with participation or follow-up in the cohort.

Sponsors & Collaborators

• Parc de Salut Mar: lead

Study Sites (2)

Hospital del Mar

Barcelona, Catalonia, 08041, Spain

RECRUITING

Hospital Clinic

Barcelona, Spain

RECRUITING

MeSH Terms

Conditions

Suicide

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Behavior

Central Study Contacts

Victor Perez-Sola, Dr

CONTACT

+34 933160623; vperez@psmar.cat

Matilde Elices, Dr

CONTACT

+34 933160623; melices@researchmar.net

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: April 17, 2026
• First Posted: April 28, 2026
• Study Start: September 1, 2024
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: April 28, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

ES (2)