Quadro-Iliac Plane Block Versus Wound Infiltration for Postoperative Pain After Single-Level Lumbar Discectomy

NCT07237945 | Recruiting

• 1 other identifier: QIPB-LD2026
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to compare the effects of the Quadro-Iliac Plane Block (QIPB) and wound infiltration (WI) on postoperative acute pain in adult patients undergoing elective single-level lumbar discectomy. QIPB is a newly introduced ultrasound-guided fascial plane block, and it is currently being used in routine clinical practice in our anesthesiology department as part of postoperative analgesia for lumbar spine surgery. Wound infiltration is a conventional method in which local anesthetic is injected into the surgical field at the end of the procedure. In this study, eligible patients will be monitored prospectively without randomization or alteration of standard care. Postoperative pain scores, opioid consumption, nausea and vomiting, patient satisfaction, and recovery parameters will be evaluated during the first 24 hours after surgery. The study aims to provide real-world clinical evidence comparing these two analgesic techniques in lumbar discectomy patients.

Conditions

Postoperative Pain Management; Lumbar Discectomy; Regional Anaesthesia

Keywords

Quadro-Iliac Plane Block; Wound Infiltration; QIPB

Outcome Measures

Primary Outcomes (1)

• 24-hour cumulative opioid consumption

  Total opioid consumption within the first 24 hours, including PCA-administered morphine and rescue analgesics converted to morphine milligram equivalents (MME).

  postoperative day 1

Secondary Outcomes (11)

• 12-hour cumulative opioid consumption

  postoperative 12th hour

• Block performance time

  intraoperative period

• Postoperative pain scores (NRS at rest and activity)

  postoperative day 1

• Patient-reported quality of recovery (QoR-15 score)

  Postoperative day 1 and at postoperative day 2-4 day

• Postoperative nausea and vomiting incidence (PONV)

  Postoperative day 1

Study Arms (2)

Group QİPB

Patients receiving ultrasound-guided Quadro-Iliac Plane Block with 30 mL of 0.25% bupivacaine per side (total 60 mL) as part of routine postoperative analgesia after single-level lumbar discectomy.

Group WI

Patients receiving ultrasound-guided wound infiltration with 20 mL of 0.25% bupivacaine into the surgical field at the end of surgery as part of routine postoperative analgesia after single-level lumbar discectomy.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients scheduled to undergo elective single-level lumbar discectomy at Karabuk Training and Research Hospital. Eligible participants will be evaluated preoperatively and enrolled prospectively according to predefined inclusion and exclusion criteria. No healthy volunteers are included.

You may qualify if:

• Adults aged 18 to 80 years
• Scheduled for elective single-level lumbar discectomy
• ASA physical status I-III
• Able to use patient-controlled analgesia (PCA)
• Able and willing to provide written informed consent

You may not qualify if:

• History of opioid use for longer than 4 weeks
• Presence of chronic pain before surgery (e.g., migraine, fibromyalgia)
• Alcohol or substance dependence
• Known allergy or hypersensitivity to local anesthetics or opioids
• Significant organ dysfunction (e.g., severe hepatic or renal disease)
• Revision or multilevel spine surgery
• Contraindications to regional anesthesia
• Severe psychiatric disorders limiting cooperation (e.g., psychosis, dementia)
• Pregnancy or breastfeeding
• Hematologic disorders

Sponsors & Collaborators

• Elif Sarikaya Ozel: lead

Study Sites (1)

Karabuk Training and Research Hospital, Department of Anesthesiology and Reanimation

Karabük, 78200, Turkey (Türkiye)

RECRUITING

Study Officials

• Elif Sarikaya Ozel

  Karabuk Training and Research Hospital, Department of Anesthesiology

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Elif Sarikaya Ozel

CONTACT

05462361453; elsarikay2@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: M.D.

Study Record Dates

• First Submitted: November 15, 2025
• First Posted: November 20, 2025
• Study Start: December 1, 2025
• Primary Completion: March 1, 2026
• Study Completion: April 1, 2026
• Last Updated: February 3, 2026

Record last verified: 2026-01

Locations

TU (1)