Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia

NCT07552116 | Recruiting

• 1 other identifier: children with pneumonia
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Conditions

Pneumonia

Keywords

Laser, Immune, Pneumonia, Dawn syndrome

Outcome Measures

Primary Outcomes (4)

• IgG

  Immunoglobulin-G (mg/dl)

  at baseline and after one month

• IgA

  Immunoglobulin-A(mg/dl)

  at baseline and after one month

• IgM

  Immunoglobulin-M (mg/dl)

  at baseline and after one month

• WBCs

  White blood cells (thousands/mm3)

  at baseline and after one month

Secondary Outcomes (2)

• RR

  at baseline and after one month

• SaO2

  at baseline and after one month

Study Arms (2)

group (A)

EXPERIMENTAL

received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month

Other: low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements; Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

group (B)

EXPERIMENTAL

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Other: received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Interventions

low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements OTHER

low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

Also known as: low intensity laser therapy, muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

group (A)

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. OTHER

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Also known as: inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

group (A); group (B)

Eligibility Criteria

• Age: 3 Years - 5 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Dawn Syndrome children with pneumonia
• Mean age of 3.73±1.82 year
• Children were in the first attack of bronchopneumonia.

You may not qualify if:

• Other chest disease

Sponsors & Collaborators

• Badr University: lead

Study Sites (1)

Mona Mohamed Abdelkhalek

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Pneumonia

Interventions

Drainage, Postural

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Drainage; Therapeutics; Physical Therapy Modalities; Rehabilitation; Respiratory Therapy

Study Officials

• Mona Mohamed Abdelkhalek, assistance prof

  Badr University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mona Mohamed Abdelkhalek, assistance professor

CONTACT

00201024056108; mona.abdelkhalek@buc.edu.eg

Mona Mohamed Abdelkhalek, assistance professor

CONTACT

00201024056108; 3m.sons@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistance professor

Model Details: Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Study Record Dates

• First Submitted: April 15, 2026
• First Posted: April 27, 2026
• Study Start: April 6, 2026
• Primary Completion (Estimated): May 30, 2026
• Study Completion (Estimated): May 30, 2026
• Last Updated: April 27, 2026

Record last verified: 2026-04

Locations

EG (1)