Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Hospital Stay in Children With Pneumonia

NCT07070271 | Not Yet Recruiting

• 1 other identifier: P.T.REC/012/005586
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to investigate the effect of respiratory neurophysiological facilitation techniques on arterial blood gases, the severity of respiratory illness and duration of hospital stay in hospitalized children with pneumonia.

Conditions

Pneumonia

Keywords

Pneumonia; Neurophysiological facilitation; Chest physical therapy; Blood gases

Outcome Measures

Primary Outcomes (3)

• Arterial blood gases

  Blood gas analysis is a commonly used diagnostic tool to evaluate the partial pressures of gas in blood and acid-base content. The blood sample is collected from the radial artery or the femoral artery.

  At baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollment

• Duration of hospitalization

  From the date of hospital admission until the date of discharge, up to 20 days

• The severity of respiratory illness.

  Using the Pediatric Respiratory Severity Score to assess respiratory rate, wheezing, accessory muscle use, SpO2, and feeding difficulties. Each component was given 0 or 1 point and the total score was classified as mild (0-1 points), moderate (2-3 points), or severe (4-5 points)

  At baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollment

Study Arms (2)

Conventional chest physical therapy

ACTIVE COMPARATOR

Children in this group will only receive conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed).

Other: conventional chest physical therapy

Conventional chest physical therapy + Neurophysiological facilitation techniques

EXPERIMENTAL

Children in this group will receive conventional chest physical therapy program along with respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction).

Other: Respiratory neurophysiological facilitation techniques; Other: conventional chest physical therapy

Interventions

Respiratory neurophysiological facilitation techniques OTHER

The respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction) once a day for 5 days.

Conventional chest physical therapy + Neurophysiological facilitation techniques

conventional chest physical therapy OTHER

conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed) once a day for 5 days.

Conventional chest physical therapy; Conventional chest physical therapy + Neurophysiological facilitation techniques

Eligibility Criteria

• Age: 6 Months - 2 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children of both sexes, with age ranged from 6 months to 2 years old.
• All children diagnosed with pneumonia.
• All children should be vitally stable during the study period.

You may not qualify if:

• Medically unstable children.
• Children with uncontrolled convulsions.
• Children with Osteopenia.

Sponsors & Collaborators

• Asmaa Ahmed Abd El-samad: lead

Study Sites (1)

Cairo university specialized pediatric hospital (Abo-El Reesh)

Giza, Egypt

Location

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Asmaa Ahmed Abd El-samad, master's degree

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Asmaa Ahmed Abd El-samad, master's degree

CONTACT

+201143185254; asmaasima20@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 1, 2025
• First Posted: July 17, 2025
• Study Start: August 1, 2025
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: July 17, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)