Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia

NCT06835842 | Recruiting DMC

• 1 other identifier: PT REC/012/005446
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters from mechanical ventilator in patients with pneumonia • HYPOTHESES: It will be hypothesized that there may be significant effect of rib mobilization on weaning parameters from mechanical ventilator in patients with pneumonia. RESEARCH QUESTION: Does rib mobilization have an effect on weaning parameters from mechanical ventilator in patients with pneumonia? measuring weaning parameters: on screen of mechanical ventilator : measuring respiratory rate, Tidal volume (TV), FiO2.

• Arterial blood gases (ABG) analyzer machine ABG is recorded daily (PH- PaO2 - PaCO2)
• Length of ICU stay: calculated by (admission date - discharge date
• Weaning success rate

Conditions

Pneumonia

Outcome Measures

Primary Outcomes (3)

• Arterial blood gases

  • Arterial blood gases (ABG): (PH -PaO2 - PaCO2) • PaO2/FiO2 ratio (P/F): One element of predicting successful weaning from mechanical ventilation is PaO2/FiO2 \> 200

  at least 10 consecutive days

• Respiratory rate (RR)

  It will be measured using a mechanical ventilator.

  at least 10 consecutive days

• Tidal volume (TV)

  It will be measured using a mechanical ventilator.

  at least 10 consecutive days

Secondary Outcomes (1)

• Length of hospital stay

  at least 10 consecutive days

Study Arms (2)

rib mobilization technique and routine chest physiotherapy group

EXPERIMENTAL

1.rib mobilization technique and routine chest physio therapy group: the patients will receive rib mobilization technique in addition to their medical treatment and routine chest physiotherapy for at least 30 minutes once daily for ten consecutive days

Other: rib mobilization technique; Other: routine chest physiotherapy

routine chest physiotherapy group

ACTIVE COMPARATOR

routine chest physiotherapy group : the patients in this group will receive routine chest physical therapy for at least 30 minutes once daily for 10 consecutive days

Other: routine chest physiotherapy

Interventions

rib mobilization technique OTHER

rib mobilization technique The patient in experimental group will be relaxed in semi- fowler position while connected to mechanical ventilator, therapist will seat at the patient "side, his fingers pads are placed at the position of the patient's rib angles , pulling upward and the lateral position the position is held while wait for the soft tissues to release this take from 15 seconds .Release of the diaphragm through manual contact with hypothenar region of therapist thumb inferior laterally xiphoid process and rest along Antero lateral costal margin below rib7 during exhalation the therapist thumb give pressure posteriorly repeat this steps for 3 to5 respiratory cycle • routine chest physiotherapy percussion on chest wall its frequency should be 3-7 beats per sec. vibration applying a light pressure with hand on affected segment for about 5 min modified postural drainage R. and L. side. U\&L limb passive ex. for R.10 x3 set .this program for 30 minutes once daily for ten days

rib mobilization technique and routine chest physiotherapy group

routine chest physiotherapy OTHER

routine chest physiotherapy the patient will be laid in half supine position connected to a ventilator applying * percussion on chest wall its frequency should be 3-7 beats per second or 180-420 beats per minute * vibration applying a light pressure with flattened hand on affected segment for about 5 minutes * modified postural drainage (right and left sidling 10 min for each side * upper and lower limb exercise for 4 limbs (3 sets and each set has 10 repetition * this program for 30 minutes once daily * for 10 consecutive days

rib mobilization technique and routine chest physiotherapy group; routine chest physiotherapy group

Eligibility Criteria

• Age: 40 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patient's age ranged from 40- 50 years old from both genders.
• Diagnosed with pneumonia and need invasive mechanical ventilation support.
• Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).
• mean arterial pressure \> 75 mmHg and urine output \> 1 mL/kg/h;
• Patients with Glasgow coma scale (GCS) \> 8T
• Unconscious and semi-conscious patients. -

You may not qualify if:

• Unstable hemodynamics
• Unstable neurological problems e.g. (epileptic seizures -hyperthermia).
• Unstable chest wall e.g. (multiple rib or vertebral fractures)
• Increase intracranial pressure (\>20 mmHg for \>5 min).
• Undrained pneumothorax, recent pulmonary surgery

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

El Galaa Military Hospital

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Azza Abd El Aziz Abd El Hady, professor

  Cairo University

  STUDY CHAIR

• Mohammed Abd Hakim El-Nadi, professor

  Cairo University

  STUDY DIRECTOR

Central Study Contacts

hoda gaber el said, master

CONTACT

01100272020; huda.eaid68@gmail.com

. Shymaa Mohamed Ali, lecturer

CONTACT

01144242511; shymaaali@pt.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: February 9, 2025
• First Posted: February 19, 2025
• Study Start: March 10, 2025
• Primary Completion: February 10, 2026
• Study Completion: May 20, 2026
• Last Updated: July 10, 2025

Record last verified: 2025-07

Locations

EG (1)