Evaluating Weight Loss Outcomes in Patients With Overweight or Obesity

NCT07551193 | Active Not Recruiting DMC

• 1 other identifier: ADMC-WL-2025-01
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to evaluate weight loss outcomes in adults with overweight or obesity using weight management medications. The main questions it aims to answer are: (1) How much weight do patients lose after 12 months? (2) Do blood sugar and cholesterol levels improve? (3) How safe and tolerable are these medications? This is a retrospective study using existing medical records and pharmacy claims. Participants will not be asked to do anything new; all data will be collected from routine clinical care.

Conditions

Overweight and Obesity

Keywords

obesity

Outcome Measures

Primary Outcomes (1)

• Absolute Weight Change

  Absolute weight change (kg) from baseline to 12 months

  Baseline to 12 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients (≥18 years) with overweight or obesity (BMI ≥25) who received weight management medications. Patients must have continuous insurance enrollment for 12 months before and after treatment initiation, and weight measurements at both baseline and 12 months.

You may qualify if:

• Age: Adults aged 18 years or older.
• Body Mass Index (BMI): Patients classified as overweight (BMI 25-29.9 kg/m²) or obese (BMI ≥30 kg/m²).
• Medication: At least one pharmacy claim for any approved weight management medication
• Continuous Enrollment: Patients must have continuous enrollment in medical and pharmacy insurance for 1 year prior to the index date (date of treatment initiation) and 1 year afterward.

You may not qualify if:

• Type 1 Diabetes: Patients with a diagnosis of type 1 diabetes.
• Non-Compliance: Evidence of non-compliance with treatment (e.g., gaps in therapy greater than 30 days).
• Bariatric Surgery: Patients who have undergone bariatric surgery in the past 5 years.
• Serious Comorbidities: Presence of serious medical conditions that may confound weight loss outcomes (e.g., uncontrolled psychiatric disorders, cancer).

Sponsors & Collaborators

• Aldafter Medical Center, Bahrain: lead

Study Sites (1)

AlDafter Medical center

Manama, Bahrain

Location

MeSH Terms

Conditions

Overweight; Obesity

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist

Study Record Dates

• First Submitted: April 20, 2026
• First Posted: April 24, 2026
• Study Start: October 25, 2025
• Primary Completion (Estimated): June 25, 2026
• Study Completion (Estimated): October 30, 2026
• Last Updated: April 24, 2026

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

BA (1)