NCT05987306

Brief Summary

The goal of clinical trial is to test a novel weight loss approach combining a standard weight loss and internalized weight bias intervention with self-compassion exercises in overweight adults with moderate to high levels of internalized weight bias. The main question\[s\] it aims to answer are: 1) Can participants lose significant weight loss and 2) significantly reduce internalized weight bias. Participants will take part in a 12 week novel weight loss approach combining a standard weight loss and internalized weight bias intervention with self-compassion exercises using videoconferencing software.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 25, 2023

Completed
20 days until next milestone

First Posted

Study publicly available on registry

August 14, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

September 24, 2023

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2024

Completed
Last Updated

November 14, 2023

Status Verified

November 1, 2023

Enrollment Period

7 months

First QC Date

July 25, 2023

Last Update Submit

November 10, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Weight (lbs)

    Change in weight or percent body weight

    12 weeks

  • Weight Bias Internalization Scale

    Change in internalized weight bias (range 1-7 with higher scores indicating greater internalized weight bias)

    12 weeks

Study Arms (1)

Intervention

EXPERIMENTAL

a standard weight loss and internalized weight bias intervention with self-compassion exercises

Behavioral: Weight loss plus self-compassion

Interventions

A novel weight loss approach combining a standard weight loss based on the Diabetes Prevention Program and internalized weight bias intervention with self-compassion exercises.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • BMI ≥ 25, ≥ 18 years old
  • Smartphone access
  • WBIS score ≥ 4

You may not qualify if:

  • Type I diabetes, uncontrolled hypertension, cardiovascular event in past year, any major active kidney, liver, cardio, or cerebrovascular disease,
  • musculoskeletal problems that would prevent physical activity,
  • current weight loss medication or weight loss program,
  • history of bariatric surgery,
  • pregnant or breastfeeding,
  • eating disorder except binge eating disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

East Carolina University

Greenville, North Carolina, 27858, United States

NOT YET RECRUITING

ECU, Dept of Psychology, 104 Rawl

Greenville, North Carolina, 27858, United States

RECRUITING

MeSH Terms

Conditions

OverweightObesity

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Robert Carels

    East Carolina University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Robert Carels

CONTACT

Abbie Metzler

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Single group pre and posttest design.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 25, 2023

First Posted

August 14, 2023

Study Start

September 24, 2023

Primary Completion

May 1, 2024

Study Completion

May 1, 2024

Last Updated

November 14, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will share

I am happy to make data available to qualified researchers.

Locations