Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury

NCT07549087 | Not Yet Recruiting

• 1 other identifier: istftreah12
• Study Type: observational
• Target: 128
• Locations: 1 country
• Sites: 1

Brief Summary

Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study. Demographic and clinical data of the participants, including age, sex, height, weight, etiology of injury, level of injury, duration of injury, and comorbidities, will be recorded. In addition, disease-specific characteristics such as ambulation status, wheelchair use, presence of incontinence, and presence and severity of pain will be assessed. For the healthy control group, demographic data including age, sex, height, weight, and comorbidities will be recorded. Motor imagery performance of the participants will be evaluated using a computer-based left/right judgment task. In this context, both upper extremity (hand) and lower extremity (foot) images will be used to record reaction time (motor imagery reaction time) and accuracy rate. All tests will be performed under standardized conditions, in a seated position, and using the same device.

Conditions

Spinal Cord Injuries

Outcome Measures

Primary Outcomes (2)

• Motor Imagery Reaction Time - Upper Extremity

  Reaction time (in milliseconds) required to correctly identify left or right hand images in a computer-based motor imagery task. Longer reaction times indicate impaired motor imagery processing.

  Baseline

• Motor Imagery Reaction Time - Lower Extremity

  Reaction time (in milliseconds) required to correctly identify left or right foot images. Higher values indicate slower motor imagery performance.

  Baseline

Secondary Outcomes (3)

• Functional Independence

  Baseline

• Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A)

  Baseline

• Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)

  Baseline

Study Arms (2)

SCI group

Patients with spinal cord injury

Other: No intervention

Control group

Healthy controls

Other: No intervention

Interventions

No intervention OTHER

No intervention

Control group; SCI group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will consist of individuals aged 18-65 years with a clinical diagnosis of spinal cord injury and paraplegia who are followed in the inpatient and outpatient clinics of Istanbul Physical Therapy and Rehabilitation Training and Research Hospital. A healthy control group, matched for age and sex, will also be included. Participants will be recruited from patients presenting to the clinic during the study period and from healthy volunteers. All participants will be medically stable and able to complete the study assessments.

You may qualify if:

• Aged between 18 and 65 years
• Clinically diagnosed with spinal cord injury
• Presence of paraplegia
• Injury duration of at least 3 months
• Medically stable condition
• Ability to understand and follow study instructions
• Ability to complete the computer-based left/right judgment task
• Willingness to participate and provide written informed consent
• For the healthy control group: age- and sex-compatible individuals without a history of neurological or major musculoskeletal disease, willing to participate and provide written informed consent

You may not qualify if:

• Tetraplegia
• History of other neurological disorders that may affect motor imagery performance
• Severe cognitive impairment or communication problems preventing proper participation
• Severe visual impairment uncorrected by glasses or lenses
• Upper or lower extremity musculoskeletal disorders, deformities, or recent injuries that may affect task performance
• Severe psychiatric disorder
• Uncontrolled pain or acute medical condition at the time of assessment
• Current participation in another interventional clinical study

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine and Rehabilitation Trainig and Research Hospital

Istanbul, Bahcelievler, 34100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 18, 2026
• First Posted: April 23, 2026
• Study Start: April 20, 2026
• Primary Completion (Estimated): May 20, 2026
• Study Completion (Estimated): May 20, 2026
• Last Updated: April 23, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)