NCT07540780

Brief Summary

The purpose of this study is to pilot test feasibility and acceptability of the Quit the Hit Toolkit, a social media-based nicotine vaping cessation program for adolescents and young adults, adapted for use in community settings.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
3mo left

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress21%
Apr 2026Aug 2026

First Submitted

Initial submission to the registry

April 14, 2026

Completed
1 day until next milestone

Study Start

First participant enrolled

April 15, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 20, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2026

Expected
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

4 months

First QC Date

April 14, 2026

Last Update Submit

April 18, 2026

Conditions

Keywords

single armpilotinterventionvapingadolescentyoung adult

Outcome Measures

Primary Outcomes (1)

  • Number of coaches who complete training and coach a vaping cessation group for 5 weeks

    Participants will be trained to serve as group coaches, implementing the intervention ("Quit the Hit Toolkit") to help teens and young adults stop vaping. Coaches will complete training and each will recruit approximately 10 participants for a vaping cessation group for 5 weeks. Investigators will track the number of coaches who successfully complete both training, recruit participants, and coach the groups for 5 weeks.

    5 weeks

Secondary Outcomes (3)

  • Number of participants recruited and enrolled in the pilot study

    From time that coaches complete training to pilot group kickoff not greater than 4 weeks

  • Number of participants who complete vaping cessation group over 5 weeks

    From start of cessation groups to end of the intervention over 5 weeks.

  • Acceptability of training protocol and intervention procedures to coaches and participants measured by qualitative interviews

    Following the end of pilot groups over about 2 weeks

Study Arms (1)

Vaping Intervention

EXPERIMENTAL

Individuals will receive training on how to implement the vaping intervention (Quit the Hit Toolkit) in their own community settings. These individuals will serve as coaches and will recruit and facilitate vaping support groups on Instagram, where group participants will receive up to 3 Instagram posts per day for 30 days. Group coaches will work with a Cessation Counselor, Principal Investigator, Co-Investigators and a Pediatrician on demand if additional expertise or clinical advice is needed. Group participants will be educated about signs of nicotine dependence and if they express interest in pharmacotherapy will be encouraged to access this through their personal healthcare providers. The Instagram groups will provide educational and social support, troubleshooting and advice about nicotine replacement therapy (NRT) or other forms of treatment. Groups will also include trained peer mentors to provide additional support.

Behavioral: Social Media Intervention

Interventions

Social media based intervention using Instagram with up to 3 posts per day for 30 days

Vaping Intervention

Eligibility Criteria

Age13 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • English literacy
  • Age between 13-21 years (group participants) or 18+ (coaches, peer mentors)
  • Indicate they use social media "most" (\>= 4) days per week (group participants)
  • Have vaped at least once per week in the past 30 days (90 percent of participants) (group participants)
  • Access to a computer or mobile phone with photo capability to verify abstinence from vaping (group participants)
  • Indicate they are considering quitting or are interested in quitting with the next 6 months or within the next 30 days (group participants)
  • Currently reside in California, Minnesota, Oklahoma, or South Carolina

You may not qualify if:

  • No English literacy
  • Age under 13 or over 21 (group participants) or under 18 (coaches, peer mentors)
  • Insufficient social media use (3 or fewer days per week) (group participants)
  • Have not vaped at least once per week in past 30 days (group participants)
  • No access to computer or mobile phone with photo capability to verify abstinence from vaping (group participants)
  • Not considering or interested in quitting vaping in the next 30 days or 6 months (group participants)
  • Not a resident of California, Minnesota, Oklahoma, or South Carolina

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94143, United States

RECRUITING

Related Publications (2)

  • Lyu JC, Olson SS, Ramo DE, Ling PM. Delivering vaping cessation interventions to adolescents and young adults on Instagram: protocol for a randomized controlled trial. BMC Public Health. 2022 Dec 10;22(1):2311. doi: 10.1186/s12889-022-14606-7.

    PMID: 36496358BACKGROUND
  • Ling PM, JoanneLyu C, Lisha NE, NhungNguyen, ValerieGribben, DanielleRamo. Social media support groups for youth nicotine vaping cessation: a randomized clinical trial. Am J Prev Med. 2026 Feb 20:108314. doi: 10.1016/j.amepre.2026.108314. Online ahead of print.

    PMID: 41724253BACKGROUND

Related Links

MeSH Terms

Conditions

VapingTobacco Use Disorder

Condition Hierarchy (Ancestors)

SmokingBehaviorSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Study Officials

  • Pamela M Ling, MD, MPH

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sarah Rosen, BA

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine

Study Record Dates

First Submitted

April 14, 2026

First Posted

April 20, 2026

Study Start

April 15, 2026

Primary Completion (Estimated)

July 31, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

April 23, 2026

Record last verified: 2026-04

Locations