Cross Modal Correlation of EEG and MRI Functional Connectivity: An Investigative Study

NCT07539506 | Recruiting

• 1 other identifier: 0287-23-ASF
• Study Type: interventional
• Target: 1,500
• Locations: 1 country
• Sites: 1

Brief Summary

Cross modal correlation of EEG and MRI functional connectivity: An Investigative Study. Correlating EEG Analysis with Brain Network Connectivity in Functional MRI. The primary aim of this study is to correlate correlation of MRI and EEG.

Conditions

MRI, Functional MRI

Keywords

Fmri; EEG

Outcome Measures

Primary Outcomes (1)

• Correlation of fMRI and EEG functional connectivity.

  Examines how brain connectivity patterns measured by fMRI (blood-flow activity) relate to connectivity patterns measured by EEG (electrical activity).

  The expected study duration is approximately 24 months (first patient in to last patient out)

Secondary Outcomes (2)

• Correlation between EEG to anatomical MRI findings

  The expected study duration is approximately 24 months (first patient in to last patient out)

• Correlation between EEG to clinical diagnosis, cognitive and physical parameters.

  The expected study duration is approximately 24 months (first patient in to last patient out)

Study Arms (1)

Electroencephalography (EEG)

OTHER

EEG excels in capturing rapid changes in neural activity, making it ideal for investigating the dynamic nature of brain networks. It can detect millisecond-level fluctuations in electrical brain signals, allowing precise timing of neural events and interactions between brain regions.

Diagnostic Test: EEG

Interventions

EEG DIAGNOSTIC_TEST

EEG uses small sensors paced on the scalp to record the brain's electrical activity.

Electroencephalography (EEG)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male or females aged 18 years or older.
• Performed a brain MRI at the Sagol Center MRI Unit, at the Shamir Medical Center
• Able to cooperate in an EEG evaluation
• Can read and sign the informed consent.

You may not qualify if:

• Any scalp/bone abnormality incompatible with the EEG electrodes
• Any known allergy to metals.
• Inability to cooperate with simple instructions.
• Inability to read and sign the informed consent.

Sponsors & Collaborators

• Assaf-Harofeh Medical Center: lead

Study Sites (1)

The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)

Zrifin, 70300, Israel

RECRUITING

MeSH Terms

Interventions

Electroencephalography

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Neurological; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis

Study Officials

• Shai Efrati, MD

  Study Principal Investigator

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Shai Efrati, MD

CONTACT

972509212866; efratishai@outlook.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 25, 2026
• First Posted: April 20, 2026
• Study Start: April 2, 2024
• Primary Completion (Estimated): January 31, 2030
• Study Completion (Estimated): January 31, 2030
• Last Updated: April 22, 2026

Record last verified: 2026-04

Locations

IL (1)