NCT02408627

Brief Summary

The goal of this project is the development of an EEG-cap (min. 21 electrodes) with user-friendly active dry electrodes that meets the expectations of the users regarding comfort and esthetics, without losing sight of the functional and technical demands for recording high quality EEG signals. The purpose is to use the EEG-cap to investigate clinical neurological disorders (e.g. epilepsy). The EEG-cap could also be used at home so that hospital admission in the EMU can be avoided for some patients and an increasing number of patients can be examined. Phase 3 of the Project will be divided into a Phase 3a and Phase 3b. Phase 3a of the project will comprise of an EEG-registration with the different types of electrodes in epilepsy patients with prominent interictal epileptiform discharges (IEDs) on EEG. For each epilepsy patient the EEG-recording with dry electrodes will be compared to the EEG-recordings with conventionally used wet electrodes (bridge and cup electrodes). Each EEG-recording will take approximately 10 minutes. Minimum 2 - maximum 10 epilepsy patients will be included. There will be an visual and clinical evaluation of the EEG-signals (blinded) and a technical evaluation of the EEG-signals. User experience will also be collected.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 31, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 3, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
Last Updated

November 28, 2017

Status Verified

November 1, 2017

Enrollment Period

9 months

First QC Date

March 31, 2015

Last Update Submit

November 27, 2017

Conditions

Outcome Measures

Primary Outcomes (3)

  • EEG signal quality (visual and clinical) (scale)

    10 minutes

  • EEG signal quality (technical) (signal to noise ratio)

    10 minutes

  • User experience (questionnaire)

    10 minutes

Study Arms (3)

conventional EEG-registration type 1

ACTIVE COMPARATOR

conventional EEG-registration with wet bridge electrodes and conductive gel

Device: EEG

conventional EEG-registration type 2

ACTIVE COMPARATOR

conventional EEG-registration with wet cup electrodes and collodion

Device: EEG

EEG-registration with dry electrodes

EXPERIMENTAL

EEG-registration with dry electrodes

Device: EEG

Interventions

EEGDEVICE
EEG-registration with dry electrodesconventional EEG-registration type 1conventional EEG-registration type 2

Eligibility Criteria

Age6 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Epilepsy patients with prominent interictal epileptiform discharges (IEDs) on EEG

You may not qualify if:

  • Epilepsy patients with no prominent interictal epileptiform discharges (IEDs) on EEG

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Ghent

Ghent, 9000, Belgium

Location

MeSH Terms

Conditions

Epilepsy

Interventions

Electroencephalography

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, NeurologicalDiagnostic Techniques and ProceduresDiagnosisElectrodiagnosis

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
DIAGNOSTIC
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. dr. Kristl Vonck

Study Record Dates

First Submitted

March 31, 2015

First Posted

April 3, 2015

Study Start

January 1, 2015

Primary Completion

October 1, 2015

Study Completion

October 1, 2015

Last Updated

November 28, 2017

Record last verified: 2017-11

Locations