KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice

NCT07528963 | Enrolling By Invitation

• 2 other identifiers: STUDY00160108U01CA290664
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

Rural cancer survivors experience a higher risk of negative health outcomes and require coordinated care to address the many effects of cancer and its treatment. Primary care providers recognize the importance of providing high-quality, evidence-based survivorship care and are well-positioned to meet survivor needs, however, these needs are often unmet due to limitations in knowledge, lack of resources, and administrative demands. Practical strategies are needed to help PCPs improve cancer survivorship care, and this proposal will test implementation strategies to optimize the adoption of evidence-based practices for cancer survivorship care in rural primary care settings.

Conditions

Cancer Survivorship; Primary Care

Keywords

cancer survivorship; primary care practice

Outcome Measures

Primary Outcomes (1)

• Provider Adherence to Cancer Survivorship Guidelines Measured by EHR-Based Composite Adherence Score

  The primary outcome is provider adherence to evidence-based cancer survivorship guidelines, measured using a composite score derived from electronic health record (EHR) data abstraction. The composite score assesses concordance between documented care and National Comprehensive Cancer Network (NCCN) survivorship guidelines across multiple domains (e.g., tumor surveillance, distress screening, BMI assessment, tobacco use screening, family history of cancer documentation, osteoporosis screening, and hereditary cancer risk assessment). Scores are calculated based on the proportion of eligible guideline-concordant care processes completed for each patient and aggregated at the clinic level.

  Assessed at baseline, 6, 12, and 24 months

Study Arms (3)

Virtual Scribe Medical Assistant

ACTIVE COMPARATOR

Virtual scribe medical assistants will engage in KanSurvive 2.0 Project ECHO education assist with clinical documentation, identifying cancer survivors, and scrubbing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation.

Other: KanSurvive telementoring and education; Other: Practice facilitation for quality improvement; Other: Survivorship Care Manual; Other: Virtual scribe services

Team Based Care

ACTIVE COMPARATOR

Rural primary care practice teams will assist with clinical documentation, identifying cancer survivors, and reviewing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation.

Other: KanSurvive telementoring and education; Other: Practice facilitation for quality improvement; Other: Survivorship Care Manual

Enhanced Usual Care

PLACEBO COMPARATOR

This attention control arm will engage in KanSurvive 2.0 Project ECHO education and receive an obesity management toolkit.

Other: KanSurvive telementoring and education; Other: Obesity management toolkit; Other: Survivorship Care Manual

Interventions

KanSurvive telementoring and education OTHER

Telementoring, education, and case-based learning covering evidence-based practice guidelines for breast, colorectal, lung, and prostate cancer survivorship.

Enhanced Usual Care; Team Based Care; Virtual Scribe Medical Assistant

Practice facilitation for quality improvement OTHER

Practice facilitation will be delivered to assist with quality improvement efforts using monthly Plan Do Study Act (PDSA) cycles.

Team Based Care; Virtual Scribe Medical Assistant

Survivorship Care Manual OTHER

Printed and digital manuals will be distributed to each participating primary care practice to share with the cancer survivors they see in their clinic. The manual guides patients on how to engage more effectively with their PCP and oncology care team and reviews recommended follow-up, within a format of a "service manual" and written in lay language.

Enhanced Usual Care; Team Based Care; Virtual Scribe Medical Assistant

Virtual scribe services OTHER

Participating practices who opt-in to receive virtual scribe services.

Virtual Scribe Medical Assistant

Obesity management toolkit OTHER

The Enhanced Usual Care arm will receive a short, virtual training and toolkit on the management of obesity in primary care practice and how it relates to cancer survivorship.

Enhanced Usual Care

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Rural primary care practice (PCP) located within rural urban continuum codes (RUCC) 4-9 in Kansas
• PCPs must have multiple providers
• PCPs must have at least on medical assistant
• PCPs must have an employed medical scribe or be willing to consider employing a medical scribe using study compensation and practice revenue
• Cancer survivor data is eligible for extraction if the patient is a breast, prostate, lung, and/or colorectal cancer survivor and considered to have a "reasonable likelihood" of 24-month survival by a practice provider.

You may not qualify if:

• PCPs not located within RUCC 4-9 in Kansas
• PCPs without multiple providers
• PCPs without a medical assistant
• PCPs without a medical scribe or unwilling to consider employing one
• Cancer survivorship data is ineligible for extraction is the patient is \<18 years of age or \>75 years of age, is currently receiving hospice services, or has a history of cancer other than breast, prostate, lung, or colorectal.

Sponsors & Collaborators

• University of Kansas Medical Center: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

University of Kansas Medical Center

Kansas City, Kansas, 66160, United States

Location

MeSH Terms

Interventions

Educational Status; Quality Improvement

Intervention Hierarchy (Ancestors)

Socioeconomic Factors; Population Characteristics; Engineering; Technology, Industry, and Agriculture; Quality of Health Care; Health Services Administration

Study Officials

• Allen K Greiner, MD, MPH

  University of Kansas Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 8 rural primary care practices will be randomized to the Virtual Scribe Medical Assistant arm, 4 rural primary care practices will be randomized to the Team-Based Care arm, and 4 rural primary care practices will be randomized to the Enhanced Usual Care control arm.

Study Record Dates

• First Submitted: April 15, 2025
• First Posted: April 14, 2026
• Study Start: June 30, 2025
• Primary Completion (Estimated): August 1, 2028
• Study Completion (Estimated): June 30, 2029
• Last Updated: June 18, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Start date: June 2026 End date: June 2029
• Access Criteria: De-identified study data will be made available as public use data to the research community via Open Science Framework.

Locations

US (1)