Socket Shield Technique With CGF and Xenograft for Immediate Implants

NCT07520513 | Not Yet Recruiting

• 1 other identifier: OMFS-3-3-20
• Study Type: interventional
• Target: 7
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective case series aims to evaluate the clinical and radiographic outcomes of immediate implant placement using the socket shield technique combined with concentrated growth factors (CGF) and xenograft in the esthetic zone. The study will assess crestal bone level changes and implant stability over a 6-month follow-up period.

Conditions

Immediate Dental Implant Placement; Xenograft; Alveolar Bone Preservation; Alveolar Bone Loss; Bone Resorption; Concentrated Growth Factors; Socket Shield Technique

Keywords

immediate implants; socket shield technique; Concentrated growth factor; Xenograft

Outcome Measures

Primary Outcomes (1)

• crestal bone level

  Evaluation of changes in crestal bone level around the dental implant using cone-beam computed tomography (CBCT). Measurements will be taken from a fixed reference point on the implant to the first bone-to-implant contact recorded in millimeters (mm)

  2 weeks, and 6 months postoperatively

Secondary Outcomes (1)

• Implant Stability (ISQ Values)

  Immediate postoperative, and at 6 months

Study Arms (1)

Socket Shield Technique with CGF and Xenograft in Immediate Implant Placement

EXPERIMENTAL

Participants will undergo immediate implant placement in the esthetic zone using the socket shield technique. Following partial extraction therapy, implants will be placed immediately, and the jumping gap will be filled using a combination of concentrated growth factors (CGF) and xenograft prepared as "sticky bone." Clinical and radiographic follow-up will be conducted over a 6-month period to evaluate crestal bone levels and implant stability.

Procedure: Socket Shield Technique with Immediate Implant Placement and CGF + Xenograft

Interventions

Socket Shield Technique with Immediate Implant Placement and CGF + Xenograft PROCEDURE

The procedure involves partial extraction therapy using the socket shield technique, where the buccal portion of the root is preserved to maintain the alveolar bone. Immediate implant placement is performed into the extraction socket. Concentrated growth factors (CGF) are prepared from the patient's autologous blood via centrifugation and combined with xenograft to form a "sticky bone" graft. This graft is placed in the jumping gap between the implant and socket wall to enhance bone regeneration and healing. Implant stability will be measured using resonance frequency analysis (Osstell), and radiographic evaluation will be performed using CBCT.

Socket Shield Technique with CGF and Xenograft in Immediate Implant Placement

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥18 years old. (Younis, W., \& El-Rashidy, A. 2020).
• Both male and female patients.
• Maxillary, anterior and premolar segments.

You may not qualify if:

• A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).
• Presence of active or untreated periodontal disease.
• Vertical root fractures involving the buccal aspect.
• Tooth /teeth with horizontal fractures below bone level.
• Tooth /teeth with external or internal resorption.
• Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry, Cairo University

Cairo, Cairo Governorate, 11553, Egypt

Location

MeSH Terms

Conditions

Alveolar Bone Loss; Bone Resorption

Interventions

Immediate Dental Implant Loading; Transplantation, Heterologous

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Periodontal Atrophy; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Dental Implantation, Endosseous; Dental Implantation; Oral Surgical Procedures, Preprosthetic; Oral Surgical Procedures; Surgical Procedures, Operative; Prosthesis Implantation; Dentistry; Prosthodontics; Transplantation

Study Officials

• Tarek I.A El-Ghareeb, PHD Holder

  Cairo University

  STUDY CHAIR

• Abdelmoez Mohamed EL-Sharkawy, Associate professor

  Cairo University

  STUDY DIRECTOR

Central Study Contacts

Huda Ayman Alrifai, bachelors

CONTACT

+201111373439; hoda.elrefai@dentistry.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 3, 2026
• First Posted: April 9, 2026
• Study Start: April 5, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): December 30, 2026
• Last Updated: April 13, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)