NCT07484880

Brief Summary

The goal of this clinical trial study is to evaluate the effectiveness of a board game-based serious game as a learning strategy to improve knowledge and study motivation on antibiotics and bacteria topics in undergraduate dental students at Faculty of Dentistry, Universitas Indonesia. The main questions it aims to answer are:

  • Does the "D'Antibiotika Academy" board game lead to higher post-test scores compared to traditional handout-based learning?
  • Does the board game improve students' study motivation on antibiotics and bacteria topic? Researchers will compare the board game intervention group to the traditional handout (control) group to see if the game-based approach provides superior learning outcomes and higher student engagement. Participants will:
  • Complete a pre-test to measure their baseline knowledge of bacteria and antibiotics.
  • Participate in a learning session using either the "D'Antibiotika Academy" board game or a conventional handout.
  • Complete a post-test 1 and post-test 2 immediately after the session to measure immediate knowledge gain.
  • Switch groups (crossover) after a washout period to ensure all participants experience both methods.
  • Complete a study motivation questionnaire after the completion of the sessions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 9, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2025

Completed
18 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2025

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 13, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 20, 2026

Completed
Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

2 months

First QC Date

March 13, 2026

Last Update Submit

March 18, 2026

Conditions

Keywords

Serious GameDental EducationBoard Game

Outcome Measures

Primary Outcomes (1)

  • Knowledge Score

    A knowledge assessment consisting of 40 multiple-choice questions, with 20 questions dedicated to antibiotic topics and 20 questions to bacterial topics. The maximum score is 100, where higher scores indicate better knowledge acquisition. This assessment was used on Pre-Test, Post-Test 1 and Post-Test 2.

    -) [Day 1] baseline (pre-test) -) [Days 2-3] Intervention phase 1 (2 days), followed by Post-test 1 -) [Days 4-10] Washout periods (up to 7 days) -) [Days 11-12] Intervention Phase 2 (2 days), followed by Post-test 2

Secondary Outcomes (1)

  • Learning Motivation Score (IMMS Questionnaire)

    at study completion (Days 12-14)

Study Arms (2)

HO-BG Group (Handout then Board Game)

ACTIVE COMPARATOR

Participants in this arm are provided with a digital text-based Handout-based learning during intervention phase 1 followed by board game learning during intervention phase 1

Other: D'Antibiotika Academy Board GameOther: Handout

BG-HO Group (Board Game then Handout)

EXPERIMENTAL

Participants in this arm are provided with a Board game learning during intervention phase 1, followed by handout-based learning during intervention phase 2

Other: D'Antibiotika Academy Board GameOther: Handout

Interventions

A serious board game designed for dental students to learn about antibiotic classification, mechanisms of action, resistance, and bacterial classification. The intervention is delivered in a 120-minute in two sessions supervised interactive group session.

BG-HO Group (Board Game then Handout)HO-BG Group (Handout then Board Game)
HandoutOTHER

A digital text-based learning material containing identical scientific content to the D'Antibiotika Academy board game. Participants access and study the material independently

BG-HO Group (Board Game then Handout)HO-BG Group (Handout then Board Game)

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Undergraduate dental students at the Faculty of Dentistry, Universitas Indonesia, from the class of 2022, 2023, and 2025.
  • Students who demonstrate a clear understanding of the study's explanation provided by the researchers and are willing to participate by signing the informed consent form.
  • Students who are committed to participating in all research sessions and procedures until completion

You may not qualify if:

  • Students who are unable to participate in the entire research sequence from beginning to end.
  • Students who withdraw their participation at any point during the study period.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry Universitas Indonesia

Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia

Location

Related Publications (8)

  • Holz M, Naavaal S, Stilianoudakis S, Carrico C, Byrne BE, Myers GL. Antibiotics and antimicrobial resistance: Evaluation of the knowledge, attitude, and perception among students and faculty within US dental schools. J Dent Educ. 2021 Mar;85(3):383-391. doi: 10.1002/jdd.12445. Epub 2020 Oct 12.

    PMID: 33044754BACKGROUND
  • AboAlSamh A, Alhussain A, Alanazi N, Alahmari R, Shaheen N, Adlan A. Dental Students' Knowledge and Attitudes towards Antibiotic Prescribing Guidelines in Riyadh, Saudi Arabia. Pharmacy (Basel). 2018 May 7;6(2):42. doi: 10.3390/pharmacy6020042.

    PMID: 29735914BACKGROUND
  • Valente P, Lora PS, Landell MF, Schiefelbein CS, Girardi FM, Souza Ldos R, Zanonato A, Scroferneker ML. A game for teaching antimicrobial mechanisms of action. Med Teach. 2009 Sep;31(9):e383-92. doi: 10.1080/01421590802637958.

    PMID: 19811173BACKGROUND
  • Karbownik MS, Wiktorowska-Owczarek A, Kowalczyk E, Kwarta P, Mokros L, Pietras T. Board game versus lecture-based seminar in the teaching of pharmacology of antimicrobial drugs--a randomized controlled trial. FEMS Microbiol Lett. 2016 Apr;363(7):fnw045. doi: 10.1093/femsle/fnw045. Epub 2016 Feb 23.

    PMID: 26912120BACKGROUND
  • Arayapisit T, Pojmonpiti D, Dansirisomboon K, Jitverananrangsri K, Poosontipong D, Sipiyaruk K. An educational board game for learning orofacial spaces: An experimental study comparing collaborative and competitive approaches. Anat Sci Educ. 2023 Jul-Aug;16(4):666-676. doi: 10.1002/ase.2257. Epub 2023 Feb 5.

    PMID: 36695535BACKGROUND
  • Rutledge C, Walsh CM, Swinger N, Auerbach M, Castro D, Dewan M, Khattab M, Rake A, Harwayne-Gidansky I, Raymond TT, Maa T, Chang TP; Quality Cardiopulmonary Resuscitation (QCPR) leaderboard investigators of the International Network for Simulation-based Pediatric Innovation, Research, and Education (INSPIRE). Gamification in Action: Theoretical and Practical Considerations for Medical Educators. Acad Med. 2018 Jul;93(7):1014-1020. doi: 10.1097/ACM.0000000000002183.

    PMID: 29465450BACKGROUND
  • Imwattana K, Methawirune A, Voralakkulchai I, Ngamskulrungroj P. BactoBattle: a game-based learning companion for medical bacteriology. Access Microbiol. 2023 Jun 26;5(6):acmi000608.v3. doi: 10.1099/acmi.0.000608.v3. eCollection 2023.

  • Amir LR, Leonardy IC, Dewatmoko SN, Yanuar R, Suniarti DF, Idrus E, Sipiyaruk K, Puspitawati R. Serious game as oral histology learning strategy for undergraduate dental students; crossover randomized controlled trial. BMC Oral Health. 2023 Aug 23;23(1):585. doi: 10.1186/s12903-023-03286-3.

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The outcome assessor responsible for scoring knowledge tests and questionnaire results will be blinded to the intervention sequence.
Purpose
OTHER
Intervention Model
CROSSOVER
Model Details: Participants will be randomly assigned to one of two learning sequences: Sequence 1: Board game learning followed by handout-based learning. Sequence 2: Handout-based learning followed by board game learning. Each intervention session will be conducted on separate days and separated by a one-week washout period.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer, Department of Oral Biology, Faculty of Dentistry Universitas Indonesia

Study Record Dates

First Submitted

March 13, 2026

First Posted

March 20, 2026

Study Start

September 9, 2025

Primary Completion

November 20, 2025

Study Completion

December 8, 2025

Last Updated

March 20, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be shared because the dataset contains identifiable educational records of students and institutional policies restrict public data sharing.

Locations